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Emergent "Bloody Diarrhea" Associated with the Use of Oral Cefdinir in Young Children: A Brief Report and Review of Literature.

Author: Al AttraqchiYahya, Al OklaSouad, AsaadAlhasan, KurbetSantosh, PrashanthGowda Parameshwara

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Cefdinir, an oral cephalosporin, can cause reddish-colored stools in infants who are receiving iron supplements or iron-containing formula feeds. This benign adverse drug reaction is underreported, and emergency physicians should be aware of this potential interaction to avoid unnecessary patient workup and parental anxiety.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Cefdinir is an extended-spectrum, third-generation, oral cephalosporin widely used in pediatric population to treat common bacterial infections, including otitis media and streptococcal pharyngitis. It is considered a safe and well-tolerated alternative to penicillin and macrolides. CAS...See full text at original site
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難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

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引用元：
https://doi.org/10.1016/j.jemermed.2022.12.026

データ提供：米国国立医学図書館（NLM）

Cefdinir and Bloody Diarrhea: A Case for Careful Observation

In the field of pediatrics, we strive to provide safe and effective treatments for our young patients. This case report, like a medical detective story, investigates a rare and underreported adverse drug reaction associated with the use of cefdinir, an antibiotic commonly prescribed for children. The authors present three cases of infants who developed bloody diarrhea after starting cefdinir, highlighting the importance of careful observation and attention to potential drug interactions.

Cefdinir and Iron Interactions: A Tale of Unexpected Side Effects

The study finds that the bloody diarrhea experienced by these infants was likely caused by an interaction between cefdinir and iron-containing preparations, such as supplements or formula. This finding, like a hidden sand trap in a desert landscape, emphasizes the need for vigilance in monitoring for unexpected side effects, particularly in young children who are more vulnerable to drug reactions.

Navigating the World of Pediatric Pharmacology: A Call for Vigilance

This research underscores the importance of thorough history taking and attentive monitoring for potential drug interactions, particularly in pediatric patients. By recognizing the potential for unexpected side effects and taking appropriate precautions, healthcare providers can ensure the safety and well-being of their young patients.

Dr.Camel's Conclusion

This case report serves as a reminder that even seemingly safe medications can have unexpected side effects, particularly in young children. The study highlights the importance of careful observation, thorough history taking, and vigilance in monitoring for potential drug interactions. By understanding the potential for unforeseen complications and implementing appropriate safeguards, we can ensure the safe and effective use of medications in pediatric populations.

Date :
  1. Date Completed 2023-03-14
  2. Date Revised 2023-03-28
Further Info :

Pubmed ID

36822986

DOI: Digital Object Identifier

10.1016/j.jemermed.2022.12.026

Related Literature

Article Analysis
・Side Effects of cefdinir
SNS
PICO Info
in preparation
Languages

English

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