Effects of pitavastatin on atherosclerotic-associated inflammatory biomarkers in people living with HIV with dyslipidemia and receiving ritonavir-boosted atazanavir: a randomized, double-blind, crossover study.

Author: KiertiburanakulSasisopin, PhuphuakratAngsana, SrichatrapimukSirawat, SungkanuparphSomnuek, TassaneetrithepBoonrat, WongsaArtit

Paper Details 
Original Abstract of the Article :
Chronic inflammation has been described in people living with HIV (PLHIV) receiving antiretroviral therapy (ART) despite viral suppression. Inflammation associated non-communicable diseases, including atherosclerosis, are becoming recognized complication of HIV infection. We studied the effect of pi...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9969700/

データ提供:米国国立医学図書館(NLM)

Investigating the Impact of Pitavastatin on Atherosclerotic Inflammation in People with HIV

This research explores the potential of [pitavastatin] to [reduce atherosclerotic-associated inflammation in people living with HIV (PLHIV) receiving antiretroviral therapy (ART)]. The study seeks to [understand the effects of pitavastatin on inflammatory biomarkers] in this specific population.

Pitavastatin: A Potential Solution for Atherosclerotic Inflammation in PLHIV

While the study does not provide definitive conclusions, it suggests that [pitavastatin may have a beneficial effect on reducing atherosclerotic-associated inflammation in PLHIV receiving ART]. Further research is needed to [confirm these findings and determine the optimal dosage and duration of treatment].

A New Hope for Managing Atherosclerosis in PLHIV

This research provides valuable insights into the potential of [pitavastatin for mitigating the risk of atherosclerosis in PLHIV receiving ART]. It highlights the need for [continued research to explore the potential of statins for managing cardiovascular complications in this population].

Dr. Camel's Conclusion

The journey through the desert of HIV research is fraught with challenges. While ART has transformed the landscape, new challenges arise, such as the risk of atherosclerosis. This research, like a camel carrying precious water across a parched desert, offers hope by exploring the potential of pitavastatin to combat inflammation. Though more research is needed, it's a testament to the resilience of researchers in their quest for a healthier future for PLHIV. It's a reminder that even in the most challenging environments, there's always a chance for progress, and that perseverance can lead to the discovery of life-saving treatments.
Date :
  1. Date Completed 2023-03-01
  2. Date Revised 2023-05-13
Further Info :

Pubmed ID

36849967

DOI: Digital Object Identifier

PMC9969700

Related Literature

Article Analysis
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.