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Treat-to-Target or High-Intensity Statin in Patients With Coronary Artery Disease: A Randomized Clinical Trial.

Author: , AhnChul-Min, ChoiDonghoon, HongBum-Kee, HongMyeong-Ki, HongSung-Jin, JangYangsoo, KangWoong Chol, KimByeong-Keuk, KimJung-Sun, KoYoung-Guk, LeeJin-Bae, LeeJong-Young, LeeSeung-Jun, LeeYong-Joon, YangTae-Hyun, YoonJunghan

Equivalence TrialA clinical trial designed to show that a new treatment is equivalent in efficacy/safety to an existing treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study compares two approaches to statin therapy for patients with coronary artery disease: starting with high-intensity statins versus starting with moderate-intensity statins and titrating the dose to achieve a specific LDL-C goal. Current guidelines recommend high-intensity statins, but these alternative approaches have not been directly compared in a clinical trial.
Paper Details　
Original Abstract of the Article :
In patients with coronary artery disease, some guidelines recommend initial statin treatment with high-intensity statins to achieve at least a 50% reduction in low-density lipoprotein cholesterol (LDL-C). An alternative approach is to begin with moderate-intensity statins and titrate to a specific L...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9989958/

データ提供：米国国立医学図書館（NLM）

Treat-to-Target vs. High-Intensity Statin: A Camel's Quest for Optimal Coronary Artery Disease Management

Coronary artery disease (CAD), a condition affecting the heart's blood vessels, is like a blockage in a vital desert trade route, hindering the flow of essential resources. This randomized clinical trial investigates two approaches to statin therapy for CAD: treat-to-target and high-intensity statin. The study aims to determine which approach is more effective in reducing LDL-C levels and improving overall cardiovascular health. The study is currently ongoing, and the results are eagerly awaited.

Navigating the Path to Optimal CAD Management: A Camel's Perspective

This research highlights the ongoing efforts to optimize CAD management, seeking to find the most effective and individualized treatment strategies. The quest for improved treatment approaches is like searching for a clearer path through a complex and challenging desert.

A Camel's Advice for Managing CAD

Managing CAD is a crucial aspect of cardiovascular health, akin to ensuring a smooth and reliable caravan route. Consulting with a healthcare professional to discuss treatment options and monitor progress is essential for optimal outcomes.

Dr.Camel's Conclusion

This clinical trial explores the optimal approach to statin therapy for CAD, a condition affecting millions worldwide. The study aims to determine the most effective strategy for reducing LDL-C levels and improving overall cardiovascular health. It's a reminder that the pursuit of better treatment options for chronic conditions is an ongoing journey, requiring persistent research and innovation.

Date :
  1. Date Completed 2023-04-06
  2. Date Revised 2023-09-07
Further Info :

Pubmed ID

36877807

DOI: Digital Object Identifier

PMC9989958

Related Literature

Article Analysis
・Effective treatment of statins
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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