Paper Details
- Home
- Paper Details
Case report: A <i>de novo</i> ERBB3 mutation develops in a gallbladder cancer patient carrying BRCA1 mutation after effective treatment with olaparib.
Author: BaoRun-Fa, JiaZi-Yao, LauWan Yee, LiHuai-Feng, LiMao-Lan, LiXue-Chuan, LiuFa-Tao, LiuYing-Bin, LiuYun, PengShu-You, WuWen-Guang, YangJing-Xiao, ZhangFei, ZouLu
Original Abstract of the Article :
Label="Background" NlmCategory="UNASSIGNED">Gallbladder cancer (GBC) is highly lethal and resistant to most chemotherapeutic drugs. GBC was reported to carry multiple genetic mutations such as TP53, K-RAS, and ERBB2/3. Here, we unexpectedly identified a patient with GBC harboring germline BRCA1 p.Ar...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10034383/
データ提供:米国国立医学図書館(NLM)
A New Oasis in Gallbladder Cancer Treatment: A Case of de novo ERBB3 Mutation
Gallbladder cancer, a formidable foe, is like a treacherous desert, often resistant to conventional treatments. This case report presents an intriguing scenario of a patient with gallbladder cancer carrying a germline BRCA1 mutation, highlighting the potential for a new therapeutic approach using olaparib, a PARPi inhibitor. The case showcases the complex and dynamic nature of cancer, where the desert landscape of treatment can be constantly shifting.
A New Path Through the Desert
This case report offers a glimmer of hope in the fight against gallbladder cancer. The emergence of a de novo ERBB3 mutation after olaparib treatment suggests a potential new therapeutic strategy, a beacon of hope in the desert of this aggressive disease. The case highlights the importance of personalized medicine, where tailored treatment approaches can potentially unlock a new path to success.
A Desert of Challenges, a Journey of Hope
This case report, like a desert oasis, provides a rare moment of hope in the fight against gallbladder cancer. The emergence of a de novo ERBB3 mutation and the potential for olaparib treatment offer a new avenue for exploration, a reminder that even in the most challenging landscapes, new paths to healing can emerge.
Dr. Camel's Conclusion
This case report reminds us that the fight against cancer is a constant journey of exploration. It's like a desert caravan, navigating shifting sands and seeking new sources of hope. The study offers a valuable insight into the complex and dynamic nature of cancer, demonstrating the importance of personalized medicine and continuous research in finding new pathways to healing.
Date :
- Date Completed n.d.
- Date Revised 2023-03-28
Further Info :
Related Literature
English
This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.