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Perioperative Outcomes of Patients with Bleeding Disorders Undergoing Major Surgery at an Academic Hemophilia Treatment Center.

Author: DrelichDouglass A, FrenchZachary, McKenzieSteven E, RhoadesRuben, WalshKaren, YangAmy

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This retrospective study examined the surgical outcomes of 50 individuals with bleeding disorders (PwBD) who underwent major surgery at a hemophilia treatment center (HTC). The study found that only 4.8% of procedures were complicated by major bleeding and 1.6% by non-major bleeding. The mean length of stay (LOS) was 1.65 days, and the 30-day readmission rate was 1.6%. These rates were comparable to those of non-PwBD patients in a national surgical database.
Paper Details　
Original Abstract of the Article :
Persons with bleeding disorders (PwBD) are at high risk for bleeding with invasive procedures. However, the risk of bleeding in PwBD undergoing major surgery and outcomes of patients managed perioperatively at a hemophilia treatment center (HTC) are not well described. We performed a retrospective r...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052468/

データ提供：米国国立医学図書館（NLM）

Green Tea and Oxidative Stress: A Complex Relationship

Green tea extract (GTE) is often touted for its antioxidant properties and potential health benefits. This study investigates whether GTE supplementation can reduce oxidative stress in postmenopausal women. The researchers were particularly interested in the role of genetic variations in a gene called COMT, which can affect how the body processes tea catechins, the compounds responsible for green tea's potential health effects.

Green Tea's Antioxidant Power: Not as Straightforward as We Thought

The results of the study showed that GTE supplementation did not significantly reduce levels of F2-isoprostanes, a marker of oxidative stress. This finding was unexpected and suggests that green tea's antioxidant effects might be more complex than previously thought. The study also found that COMT genotype did not significantly modify the effect of GTE supplementation on F2-isoprostanes levels.

Navigating the Nuances of Diet and Health

This study serves as a reminder that the relationship between diet and health is complex and often nuanced. While green tea has been linked to numerous health benefits, this study suggests that its impact on oxidative stress might not be as straightforward as previously assumed. It's a valuable lesson in the importance of conducting thorough research to understand the true impact of dietary interventions on health outcomes.

Dr.Camel's Conclusion

This study provides important insights into the complex relationship between green tea and oxidative stress. While green tea has been hailed for its antioxidant properties, this study suggests that its effects may be more nuanced than previously believed. It's a reminder that our understanding of nutrition and health is constantly evolving, and it's essential to stay informed about the latest research findings. Just as a camel adapts to the ever-changing desert landscape, we need to be flexible in our approach to health and well-being, keeping up with new discoveries and adjusting our habits accordingly.
Date :
  1. Date Completed 2023-03-29
  2. Date Revised 2023-03-31
Further Info :

Pubmed ID

36972481

DOI: Digital Object Identifier

PMC10052468

Related Literature

Article Analysis
・Effective treatment of bleeding disorders
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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