Combining Three Tyrosine Kinase Inhibitors: Drug Monitoring Is the Key.

Author: EvrardAlexandre, FirminNelly, LeenhardtFanny, MbatchiLitaty, QuantinXavier, ThomasQuentin Dominique

Paper Details 
Original Abstract of the Article :
A combination of tyrosine kinase inhibitors (TKIs) is likely to be a therapeutic option for numerous oncological situations due to high frequency of oncogenic addiction and progress in precision oncology. Non-small cell lung cancer (NSCLC) represents a subtype of tumors for which oncogenic drivers a...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054357/

データ提供:米国国立医学図書館(NLM)

Precision Oncology: The Power of Combining Tyrosine Kinase Inhibitors

Precision oncology is revolutionizing cancer treatment, allowing for targeted therapies tailored to individual patients' tumor characteristics. This case report highlights the use of a combination of three tyrosine kinase inhibitors (TKIs) in a patient with non-small cell lung cancer (NSCLC). The authors detail the rationale for this multi-drug approach and highlight the importance of therapeutic drug monitoring in managing toxicity and optimizing efficacy. This case report offers valuable insights into the emerging field of precision oncology, demonstrating the potential of combining TKIs for improved cancer management.

Therapeutic Drug Monitoring: A Key to Precision Oncology

The authors emphasize the crucial role of therapeutic drug monitoring in managing the complex toxicity profile of multi-TKI regimens. By monitoring plasma concentrations of each TKI, clinicians can adjust dosages to ensure optimal therapeutic exposure while minimizing side effects. This case report demonstrates the importance of personalized approaches in precision oncology, ensuring that patients receive the right treatment at the right dose.

Optimizing Cancer Treatment: A Collaborative Effort

Just as a camel relies on its caravan for support and guidance during a desert journey, so too must patients with cancer rely on their healthcare team. This case report highlights the importance of collaboration between oncologists, pharmacists, and other healthcare professionals to optimize cancer treatment and ensure optimal patient outcomes.

Dr.Camel's Conclusion

This case report provides a glimpse into the exciting future of precision oncology, where tailored treatments are becoming increasingly common. It's like a caravan traversing the desert, with each member playing a vital role in ensuring a successful journey.

Date :
  1. Date Completed 2023-03-30
  2. Date Revised 2023-12-13
Further Info :

Pubmed ID

36982592

DOI: Digital Object Identifier

PMC10054357

Related Literature

SNS
PICO Info
in preparation
Languages

English

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