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Preclinical evidence for the use of the atypical antipsychotic, brexpiprazole, for opioid use disorder.
Author: DursunSerdar M, NickolsJulia E R, TaylorAnna M W
Original Abstract of the Article :
Opioid addiction is characterized by adaptations in the mesolimbic dopamine system that occur during chronic opioid use. Alterations in dopaminergic transmission contribute to pathological drug-seeking behavior and other symptoms associated with opioid withdrawal following drug discontinuation, maki...See full text at original site
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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
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引用元：
https://doi.org/10.1016/j.neuropharm.2023.109546
データ提供：米国国立医学図書館（NLM）
Brexpiprazole: A Potential Treatment for Opioid Use Disorder
This research investigates the potential of brexpiprazole, an atypical antipsychotic, as a treatment for opioid use disorder. The study explores the effects of brexpiprazole in a mouse model of opioid dependence, examining its impact on locomotor sensitization, analgesic tolerance, opioid-induced hyperalgesia, and drug-seeking behavior. The results suggest that brexpiprazole may be effective in attenuating the development of opioid dependence and reducing drug-seeking behavior.
Brexpiprazole: A Potential Ally in the Fight Against Opioid Addiction
This study delves into the potential of brexpiprazole, an atypical antipsychotic, as a treatment for opioid use disorder. The research explores the effects of brexpiprazole in a mouse model of opioid dependence, providing encouraging evidence for its potential to mitigate the development of opioid dependence and reduce drug-seeking behavior. This study offers a promising avenue for further investigation into the therapeutic potential of brexpiprazole in managing opioid addiction.
The Shifting Sands of Opioid Addiction
Opioid addiction, like a relentless desert sandstorm, can devastate individuals and families. This research, like a beacon of hope, explores the potential of brexpiprazole, an atypical antipsychotic, in managing this challenging condition. The authors find encouraging evidence for its effectiveness in reducing drug-seeking behavior and attenuating the development of opioid dependence. This study offers a glimmer of hope in the ongoing battle against opioid addiction.
Dr. Camel's Conclusion
This study highlights the potential of brexpiprazole as a promising treatment for opioid use disorder. The research provides encouraging evidence for its effectiveness in mitigating the development of opioid dependence and reducing drug-seeking behavior. It is a reminder that the journey through opioid addiction, like a desert trek, requires innovative strategies and persistent efforts to find solutions that support recovery and healing.
Date :
- Date Completed 2023-05-15
- Date Revised 2023-05-18
Further Info :
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English
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