Sinonasal malignancies: histopathological entities, regional involvement and long-term outcome.

Author: AnschuetzLukas, CaversaccioMarco, ElicinOlgun, GigerRoland, HohenbergerRalph, KaeckerChristoph

Paper Details 
Original Abstract of the Article :
BACKGROUND: To assess a large patient cohort with sinonasal malignancies focusing on regional involvement, recurrence and oncological outcome. METHODS: Patients (n = 144) with malignant tumors of the nasal cavity and paranasal sinuses were treated at our tertiary referral center between 2008 and 20...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148547/

データ提供:米国国立医学図書館(NLM)

Delving into the Depths of Sinonasal Malignancies

This research dives into the vast desert of sinonasal malignancies, seeking to unravel the complexities of these tumors. Utilizing a comprehensive patient cohort spanning over a decade, the study employed a meticulous chart review to investigate regional involvement, recurrence, and long-term outcomes. The researchers unearthed intriguing findings, particularly highlighting the prevalence of squamous cell carcinoma (SCC) as the most frequent histological type, followed by adenocarcinoma and mucosal melanoma.

Uncovering the Hidden Patterns of Recurrence

This study reveals the intricate dance of recurrence in sinonasal malignancies. Notably, a significant proportion of patients (43.1%) experienced a relapse following curative therapy, with loco-regional recurrence accounting for a notable percentage. The findings suggest that SCC exhibits a propensity for (loco-)regional recurrence, a phenomenon that demands further investigation.

Navigating the Uncertainties of Treatment

The study highlights the lack of definitive guidelines for managing these tumors. The scarcity of evidence underscores the need for further exploration of effective treatment strategies for sinonasal malignancies. This research serves as a crucial stepping stone for future studies, urging us to continue our quest for knowledge in this challenging domain.

Dr. Camel's Conclusion

The study of sinonasal malignancies is like navigating a vast, shifting desert, with each case a unique oasis. This research provides valuable insights into the terrain, identifying key features like recurrence patterns and highlighting the need for further research to guide our path towards effective treatment.

Date :
  1. Date Completed 2023-05-01
  2. Date Revised 2023-05-02
Further Info :

Pubmed ID

37118840

DOI: Digital Object Identifier

PMC10148547

Related Literature

SNS
PICO Info
in preparation
Languages

English

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