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Sinonasal malignancies: histopathological entities, regional involvement and long-term outcome.
Author: AnschuetzLukas, CaversaccioMarco, ElicinOlgun, GigerRoland, HohenbergerRalph, KaeckerChristoph
Original Abstract of the Article :
BACKGROUND: To assess a large patient cohort with sinonasal malignancies focusing on regional involvement, recurrence and oncological outcome. METHODS: Patients (n = 144) with malignant tumors of the nasal cavity and paranasal sinuses were treated at our tertiary referral center between 2008 and 20...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148547/
データ提供:米国国立医学図書館(NLM)
Delving into the Depths of Sinonasal Malignancies
This research dives into the vast desert of sinonasal malignancies, seeking to unravel the complexities of these tumors. Utilizing a comprehensive patient cohort spanning over a decade, the study employed a meticulous chart review to investigate regional involvement, recurrence, and long-term outcomes. The researchers unearthed intriguing findings, particularly highlighting the prevalence of squamous cell carcinoma (SCC) as the most frequent histological type, followed by adenocarcinoma and mucosal melanoma.
Uncovering the Hidden Patterns of Recurrence
This study reveals the intricate dance of recurrence in sinonasal malignancies. Notably, a significant proportion of patients (43.1%) experienced a relapse following curative therapy, with loco-regional recurrence accounting for a notable percentage. The findings suggest that SCC exhibits a propensity for (loco-)regional recurrence, a phenomenon that demands further investigation.
Navigating the Uncertainties of Treatment
The study highlights the lack of definitive guidelines for managing these tumors. The scarcity of evidence underscores the need for further exploration of effective treatment strategies for sinonasal malignancies. This research serves as a crucial stepping stone for future studies, urging us to continue our quest for knowledge in this challenging domain.
Dr. Camel's Conclusion
The study of sinonasal malignancies is like navigating a vast, shifting desert, with each case a unique oasis. This research provides valuable insights into the terrain, identifying key features like recurrence patterns and highlighting the need for further research to guide our path towards effective treatment.
Date :
- Date Completed 2023-05-01
- Date Revised 2023-05-02
Further Info :
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English
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