Paper Details
- Home
- Paper Details
The addition of evolocumab to maximal tolerated statin therapy improves walking performance in patients with peripheral arterial disease and intermittent claudication (Evol-PAD study).
Author: CaroJorge, CaroJorge A, ChoiJongkyu, ClavijoLeonardo C, KumarS Ram, MatthewsRay V, RoweVincent, ShavelleDavid M, TunHan
Original Abstract of the Article :
OBJECTIVE: To test the hypothesis that in patients with peripheral arterial disease (PAD) and claudication, treated with maximal tolerated statin therapy, the addition of a monthly subcutaneous injection of evolocumab for 6 months improves treadmill walking performance. BACKGROUND: Lipid lowering t...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1016/j.carrev.2023.04.020
データ提供:米国国立医学図書館(NLM)
Evolocumab: A New Oasis for Patients with Intermittent Claudication
Peripheral artery disease (PAD) is a prevalent condition that can significantly affect quality of life. Intermittent claudication, a hallmark symptom of PAD, causes pain and cramping in the legs during physical activity. This study investigates the impact of evolocumab, a cholesterol-lowering medication, on walking performance in patients with PAD and intermittent claudication. It's like exploring a new oasis in the desert of PAD treatment, seeking ways to improve the mobility and overall well-being of patients.
Improved Walking Performance with Evolocumab
The study, involving 70 patients with PAD and intermittent claudication, found that the addition of evolocumab to maximal tolerated statin therapy significantly improved maximal walking time and pain-free walking time. This suggests that evolocumab may play a valuable role in enhancing functional capacity and reducing the impact of PAD on daily life. It's like discovering an oasis that provides not only relief from thirst but also the strength to continue on the journey.
A Promising Avenue for Enhancing PAD Treatment
The study provides encouraging evidence for the potential benefits of evolocumab in PAD patients, highlighting its ability to improve walking performance and possibly slow down the progression of the disease. It's a reminder that the desert of PAD treatment is constantly evolving, and innovative approaches like evolocumab may offer new hope for a more fulfilling and mobile life for patients.
Dr.Camel's Conclusion
This study suggests that evolocumab may be a valuable addition to the treatment arsenal for PAD, offering the potential to improve walking performance and enhance the quality of life for patients with this condition. It's a reminder that the quest for better treatments for chronic conditions like PAD is an ongoing journey, and the discovery of new oases, like evolocumab, can bring renewed hope and opportunities for a healthier future.
Date :
- Date Completed 2023-11-13
- Date Revised 2023-11-13
Further Info :
Related Literature
English
This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.