Paper Details 
Original Abstract of the Article :
Wastewater-based epidemiology (WBE) is a promising technique for monitoring the rapidly increasing use of antiviral drugs during the COVID-19 pandemic. It is essential to evaluate the in-sewer stability of antiviral drugs in order to determine appropriate biomarkers. This study developed an analytic...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10149109/

データ提供:米国国立医学図書館(NLM)

Wastewater-Based Epidemiology: A Novel Tool for Monitoring Antiviral Drug Usage

In the ever-evolving landscape of drug monitoring, researchers are constantly seeking innovative approaches to understand drug usage patterns. This study explores the potential of wastewater-based epidemiology (WBE) as a powerful tool for monitoring the rapidly increasing use of antiviral drugs, particularly in the context of the COVID-19 pandemic. The authors delve into the stability of various antiviral drugs in sewage and gravity sewers, identifying suitable biomarkers for WBE.

Unveiling the Stability of Antiviral Drugs in Wastewater

The authors meticulously investigate the stability of 17 antiviral drugs in a laboratory setting, simulating the conditions found in gravity sewers. This research, like a meticulous desert expedition, provides a detailed assessment of the factors influencing the stability of these drugs in wastewater, including adsorption, biodegradation, and diffusion.

Navigating the Waters: Selecting Suitable Biomarkers for WBE

This study, like a cartographer mapping a new terrain, identifies nine antiviral drugs that are stable in wastewater, making them ideal biomarkers for WBE. The authors also propose a framework for evaluating the stability of potential biomarkers, offering valuable guidance to researchers in this rapidly evolving field.

Dr.Camel's Conclusion

This study, like a caravan venturing into a new territory, explores the potential of WBE as a novel tool for monitoring antiviral drug usage. By identifying stable biomarkers and developing a framework for evaluating their stability, this research paves the way for a more comprehensive understanding of drug use patterns in real-world settings.

Date :
  1. Date Completed 2023-05-17
  2. Date Revised 2023-05-25
Further Info :

Pubmed ID

37150064

DOI: Digital Object Identifier

PMC10149109

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.