Paper Details 
Original Abstract of the Article :
OBJECTIVE: To evaluate the efficacy and retention rate of lacosamide (LCM) over 36 months as a treatment for children and adolescents with focal and generalized epilepsy based on a retrospective study. METHODS: All patients prescribed LCM as monotherapy and add-on therapy between October 2016 and S...See full text at original site
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引用元:
https://doi.org/10.1016/j.yebeh.2023.109227

データ提供:米国国立医学図書館(NLM)

Lacosamide: Evaluating Efficacy and Retention in Epilepsy Treatment

This study explores the long-term efficacy and retention rate of lacosamide (LCM), an anti-seizure medication, in the treatment of epilepsy in children and adolescents. The study retrospectively analyzed the medical records of 126 patients who received LCM as monotherapy or add-on therapy for focal, generalized, or combined epilepsy. The researchers evaluated the response rate, retention rate, and adverse effects over a period of 36 months. The findings showed that LCM exhibited a moderate response rate but a significant decline in retention rate over time, suggesting that long-term effectiveness may vary among patients.

Navigating the Complexities of Epilepsy Treatment

This research highlights the complexities of epilepsy treatment and the challenges of finding long-term effective and well-tolerated therapies. The findings suggest that LCM may be effective for some patients but that its long-term efficacy may be limited for others. It's like a camel traversing a vast and unpredictable desert, where the path to a solution is not always straightforward.

Beyond the Sands: Personalized Approaches to Epilepsy Management

This study underscores the importance of individualized treatment approaches for epilepsy, recognizing that patients may respond differently to medications. The findings suggest that ongoing monitoring and adjustments to treatment plans may be necessary to ensure long-term efficacy. It's like a camel adapting its strategy to the changing terrain of the desert, finding the most suitable path to reach its destination.

Dr.Camel's Conclusion

This research provides valuable insights into the long-term use of lacosamide for epilepsy treatment. The findings emphasize the importance of individualized care, ongoing monitoring, and a collaborative approach between clinicians and patients to ensure the best possible outcomes. It's a reminder that the journey through the desert of epilepsy is not always smooth, but with careful navigation and a steady hand, we can find paths to relief and a better future.

Date :
  1. Date Completed 2023-06-19
  2. Date Revised 2023-11-16
Further Info :

Pubmed ID

37207404

DOI: Digital Object Identifier

10.1016/j.yebeh.2023.109227

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English

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