Tyrosine kinase inhibitor toxicities: A society of gynecologic oncology review and recommendations.

Author: CraneErin K, HouJune, LutzKathleen, MacDonaldJennifer, MakkerVicky, NakayamaJohn, O'CearbhaillRoisin E, RimelBobbie J

Paper Details 
Original Abstract of the Article :
Oral tyrosine kinase inhibitors (TKIs) have new indications for treatment in gynecologic malignancies. These targeted drugs have both unique and overlapping toxicities, which require careful attention and management. New combination therapies with immune-oncology agents have demonstrated promise in ...See full text at original site
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引用元:
https://doi.org/10.1016/j.ygyno.2023.05.007

データ提供:米国国立医学図書館(NLM)

Taming the Tyrant: Managing Tyrosine Kinase Inhibitor Toxicities

Cancer treatment is often a grueling journey, fraught with challenges. Tyrosine kinase inhibitors (TKIs), a powerful class of drugs that target specific proteins involved in cancer growth, have emerged as promising weapons in the fight against gynecologic malignancies. However, like any potent medicine, TKIs can come with a set of side effects that require careful monitoring and management. This study serves as a comprehensive guide for clinicians, providing an evidence-based review of common adverse events associated with TKIs and offering strategies for mitigating these potential complications. It's like a desert oasis providing respite and guidance for those traversing the challenging landscape of cancer treatment.

Decoding the Language of TKI Toxicities

The study provides a detailed analysis of common toxicities associated with TKIs, offering valuable insights into the potential risks and benefits of these targeted therapies. The study's findings have implications for optimizing treatment strategies and improving patient safety. It's like deciphering an ancient scroll, unveiling the hidden secrets of TKI-related adverse effects.

Finding Balance in Cancer Treatment

This study underscores the importance of balancing the potential benefits of TKIs with their associated risks. It emphasizes the need for vigilant monitoring and proactive management of side effects, ensuring that patients receive the best possible care while minimizing potential complications. It's like finding a delicate balance between the harsh realities of cancer treatment and the desire for a fulfilling life.

Dr.Camel's Conclusion

This research provides invaluable insights into the complexities of managing TKI toxicities. By understanding the potential side effects of these powerful drugs and implementing effective strategies for mitigating them, we can help patients navigate the challenging journey of cancer treatment with greater confidence and resilience.

Date :
  1. Date Completed 2023-07-03
  2. Date Revised 2023-12-13
Further Info :

Pubmed ID

37207499

DOI: Digital Object Identifier

10.1016/j.ygyno.2023.05.007

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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