Topical photodynamic therapy for brachytherapy-induced oral mucositis.

Author: CaoJunnan, ChenXue, LiuRui, WangXing, ZhangHailong

Paper Details 
Original Abstract of the Article :
Radioactive iodine-125 seed implantation has emerged as an effective treatment approach for locally advanced oral cancer. Nevertheless, some brachytherapy associated side reactions were reported, even at a relatively low initial radiation treatment volume. Radiogenic oral mucositis has been a concer...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1016/j.pdpdt.2023.103617

データ提供:米国国立医学図書館(NLM)

Photodynamic Therapy: A Light at the End of the Tunnel for Brachytherapy-Induced Mucositis

Brachytherapy, a localized radiation therapy technique, is increasingly used for the treatment of oral cancer. While effective, it can lead to a debilitating side effect called oral mucositis, characterized by inflammation and ulceration of the oral mucosa. This case report explores the use of topical photodynamic therapy (PDT) as a potential treatment for brachytherapy-induced oral mucositis. The authors describe the successful treatment of a 73-year-old male patient with oral mucositis using four sessions of topical 5-aminolevulinic acid (ALA) PDT. The patient experienced complete resolution of mucositis and remained in remission for six months following treatment.

A New Light on Mucositis Management: Photodynamic Therapy

This case report provides compelling evidence for the potential of PDT as a safe and effective treatment for brachytherapy-induced oral mucositis. The use of topical ALA-PDT offers a minimally invasive and targeted approach to managing this debilitating side effect, potentially improving patient quality of life and facilitating quicker recovery.

Improving Patient Outcomes: Harnessing the Power of Light

The use of PDT in managing oral mucositis represents a promising advancement in radiation oncology. By harnessing the power of light, PDT offers a non-invasive and targeted approach to reducing inflammation and promoting healing, potentially improving patient outcomes and minimizing the discomfort associated with mucositis. This innovation holds promise for improving the overall experience of patients undergoing brachytherapy for oral cancer.

Dr.Camel's Conclusion

Oral mucositis, a common side effect of brachytherapy, can feel like a scorching desert wind, causing pain and discomfort. This case report provides a ray of hope, highlighting the potential of photodynamic therapy to bring relief and healing to patients experiencing this challenging condition. The use of light as a therapeutic tool offers a promising avenue for improving patient outcomes and enhancing their quality of life during radiation therapy.

Date :
  1. Date Completed 2023-07-03
  2. Date Revised 2023-07-03
Further Info :

Pubmed ID

37209763

DOI: Digital Object Identifier

10.1016/j.pdpdt.2023.103617

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.