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The multifunctional human ocular melanocortin system.

Author: CioancaAdrian V, ConwayR Max, Di GirolamoNick, GelmiMaria C, JagerMartine J, MadiganMichele C, McCluskeyPeter J, NatoliRiccardo, PetsoglouConstantinos, WenLi, WuChieh-Lin Stanley, ZhuLing

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This review highlights the physiological and disease-related involvement of the melanocortin system within human eye tissues and reviews the emerging benefits and versatility of melanocortin receptor targeted peptides as non-steroidal alternatives for inflammatory eye diseases.
Paper Details　
Original Abstract of the Article :
Immune privilege in the eye involves physical barriers, immune regulation and secreted proteins that together limit the damaging effects of intraocular immune responses and inflammation. The neuropeptide alpha-melanocyte stimulating hormone (α-MSH) normally circulates in the aqueous humour of the an...See full text at original site
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引用元：
https://doi.org/10.1016/j.preteyeres.2023.101187

データ提供：米国国立医学図書館（NLM）

The Multifaceted Roles of the Ocular Melanocortin System

This study delves into the ocular melanocortin system, which plays a crucial role in maintaining the health and function of the eye. It explores the various ways this system helps regulate immune responses, promote tissue repair, and protect against inflammation. It's like uncovering a hidden network of pathways within the desert of the human eye.

The Melanocortin System: A Key to Eye Health

The study reveals that the melanocortin system is involved in a wide range of ocular functions, including maintaining corneal transparency, regulating tear production, and protecting the retina. This system can be a powerful tool for treating eye conditions, like uveitis and dry eye disease. It's like finding a magical oasis within the desert of the eye, offering a diverse array of benefits for ocular health.

Protecting Your Vision: A Desert Oasis of Knowledge

This study emphasizes the importance of understanding and preserving the delicate balance of the ocular melanocortin system. It highlights the potential for targeted therapies that utilize melanocortin receptor-specific peptides to address various eye conditions. It's like exploring a hidden oasis within the vast desert of eye health, offering a glimpse of future possibilities for treating ocular diseases.

Dr.Camel's Conclusion

This study unveils the intricate workings of the ocular melanocortin system, revealing its crucial role in maintaining eye health and providing new insights for the development of targeted therapies. It's a reminder that even in the vast and complex desert of human biology, there are often hidden pathways and solutions waiting to be discovered.
Date :
  1. Date Completed 2023-07-10
  2. Date Revised 2023-11-16
Further Info :

Pubmed ID

37217094

DOI: Digital Object Identifier

10.1016/j.preteyeres.2023.101187

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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