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Protein@Cyanine-Based NIR-II Lymphography Enables the Supersensitive Visualization of Lymphedema and Tumor Lymphatic Metastasis.
Author: DuYijing, HanTianyang, XuJiajun, ZhuNingning, ZhuShoujun
Original Abstract of the Article :
Visualization of the lymphatic system is clinically indispensable for the diagnosis and/or treatment of lymphatic diseases. Although indocyanine green (ICG) lymphography becomes an alternate imaging modality compared to traditional lymphoscintigraphy, it is still far from ideal due to the insufficie...See full text at original site
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引用元:
https://doi.org/10.1002/adhm.202301051
データ提供:米国国立医学図書館(NLM)
Protein@Cyanine-Based NIR-II Lymphography: A New Era of Lymphatic Imaging
This study explores the potential of a groundbreaking new imaging technique, protein@cyanine-based NIR-II lymphography, for visualizing the lymphatic system. The research aims to overcome the limitations of existing near-infrared-I (NIR-I) lymphography by developing novel probes that offer superior detection depth, spatial resolution, and pharmacokinetic control.
A Superior Approach: Protein@Cyanine Probes Revolutionize Lymphatic Imaging
The study demonstrates the effectiveness of protein@cyanine probes, synthesized using a chlorine-containing dye-labeling strategy, in providing exceptional NIR-II imaging capabilities. These probes excel in their ability to locate lymph nodes and delineate lymphatic vessels with high sensitivity and a strong signal-to-background ratio, enabling real-time diagnosis of lymphatic diseases like lymphedema and tumor lymphatic metastasis. The NIR-II lymphography technology allows for the detection of subtle variations in the lymphatic system, providing a deeper understanding of lymphatic health.
A Powerful Tool for Early Diagnosis and Treatment
The protein@cyanine-based NIR-II lymphography technology holds immense promise for improving diagnosis and treatment of lymphatic diseases. By providing a clearer and more detailed visualization of the lymphatic system, this technique allows for early detection of abnormalities and more targeted interventions. This, in turn, can lead to better patient outcomes.
Dr.Camel's Conclusion
This innovative research paves the way for a new era of lymphatic imaging. The protein@cyanine-based NIR-II lymphography technology promises to revolutionize our understanding of lymphatic health and disease. By providing a highly sensitive and precise visualization of the lymphatic system, this technique has the potential to significantly impact the diagnosis, treatment, and management of a wide range of lymphatic conditions. The future of lymphatic imaging is bright, and this groundbreaking technology is leading the way.
Date :
- Date Completed 2023-10-30
- Date Revised 2023-11-12
Further Info :
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