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Doravirine plus lamivudine two-drug regimen as maintenance antiretroviral therapy in people living with HIV: a French observational study.
Author: , AbdiBasma, ArvieuxCédric, DutheJean-Charles, HallNolwenn, KatlamaChristine, LamauryIsabelle, MarcelinAnne-Geneviève, MenardAmélie, PalichRomain, PerfezouPascale, SeangSophie
Original Abstract of the Article :
Two-drug regimens based on integrase strand transfer inhibitors (INSTIs) and boosted PIs have entered recommended ART. However, INSTIs and boosted PIs may not be suitable for all patients. We aimed to report our experience with doravirine/lamivudine as maintenance therapy in people living with HIV (...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1093/jac/dkad185
データ提供:米国国立医学図書館(NLM)
A New Path in the Desert of HIV Treatment
The world of HIV treatment is a vast and ever-evolving desert, where researchers are constantly seeking new oases of hope. This observational study, like a determined caravan navigating the shifting sands, explores the use of a doravirine/lamivudine two-drug regimen as maintenance antiretroviral therapy for people living with HIV (PLWH). The authors recognize the limitations of existing regimens, particularly for patients who cannot tolerate integrase strand transfer inhibitors (INSTIs) or boosted protease inhibitors (PIs), and seek to evaluate the effectiveness of this alternative approach. The study examines the real-world experience of PLWH followed in French HIV settings.
A Promising Oasis in the Desert of HIV Treatment
This study, like a well-preserved map, provides valuable insights into the potential of doravirine/lamivudine as maintenance therapy for PLWH. While further research is needed to confirm its long-term efficacy and safety, the study's findings offer a promising alternative for patients who cannot tolerate other treatment options. This research, like a refreshing spring in the desert, offers a beacon of hope for those seeking effective and tolerable HIV treatment.
Navigating the Desert of HIV Management
The desert of HIV management continues to evolve, and we must adapt our approaches to provide the most effective care for all patients. This study emphasizes the importance of exploring diverse treatment options, considering individual patient needs and preferences. We must continue our journey through the desert of HIV research, seeking new oases of hope and more personalized approaches to treatment.
Dr.Camel's Conclusion
This study offers a promising glimpse into the potential of doravirine/lamivudine as a maintenance therapy for people living with HIV. It highlights the importance of seeking alternative treatment options and underscores the need for ongoing research to develop individualized and effective therapies.
Date :
- Date Completed 2023-08-03
- Date Revised 2023-10-12
Further Info :
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English
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