Paper Details 
Original Abstract of the Article :
Dasatinib is effective in the treatment of chronic and acute myeloid leukemia, which could cause the side effect of gastrointestinal bleeding by overdose or longtime use. Ruscogenin (RUS) from the traditional Chinese medicine Ophiopogon japonicas could protect endothelial microvascular barrier funct...See full text at original site
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引用元:
https://doi.org/10.1007/s11418-023-01715-9

データ提供:米国国立医学図書館(NLM)

Ruscogenin: A Potential Ally in Combating Dasatinib-Induced Intestinal Side Effects

In the vast desert of [Pharmacology and Gastrointestinal Health], we often encounter unwanted side effects from medications. This study delves into the potential of ruscogenin, a natural compound derived from a traditional Chinese medicine, to alleviate gastrointestinal bleeding, a known side effect of the leukemia drug dasatinib. Researchers found that ruscogenin effectively protected the intestinal barrier function by regulating specific cellular pathways, suggesting its potential role in mitigating dasatinib-induced intestinal side effects.

Ruscogenin: A Potential Protective Shield

This research highlights the potential of ruscogenin, a natural compound, to alleviate gastrointestinal bleeding, a common side effect of the leukemia drug dasatinib. It's like finding a shield in the desert, protecting against the harshness of adverse drug effects. This study suggests that ruscogenin could be a valuable tool for managing the gastrointestinal side effects of dasatinib, potentially improving patient outcomes.

Navigating the Desert of Drug Side Effects

This research emphasizes the importance of seeking alternative strategies to manage drug side effects, particularly in the context of potent medications like dasatinib. It suggests that natural compounds, like ruscogenin, may offer a promising avenue for mitigating adverse effects and improving patient quality of life. It's like discovering a new oasis in the desert of drug side effects, offering a source of relief and improved well-being.

Dr.Camel's Conclusion

The study explores the potential of ruscogenin to alleviate gastrointestinal bleeding, a side effect of dasatinib, a leukemia drug. It suggests that ruscogenin may offer a promising avenue for managing dasatinib-induced intestinal side effects, potentially improving patient outcomes.

Date :
  1. Date Completed 2023-08-31
  2. Date Revised 2023-08-31
Further Info :

Pubmed ID

37347409

DOI: Digital Object Identifier

10.1007/s11418-023-01715-9

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SNS
PICO Info
in preparation
Languages

English

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