Lipid profile changes associated with antiretroviral therapies in a real-world cohort.

Author: Cid-SilvaPurificación, Fernández-OliveiraCarla, Giménez-ArufeVíctor, Margusino-FramiñánLuis, Martín-HerranzIsabel, Martínez-PradedaAlejandro, Mena-de-CeaÁlvaro, Rotea-SalvoSandra

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To compare lipid profile changes and cardiovascular events among HIV naïve and experienced patients from a real-world cohort treated with elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide fumarate or dolutegravir/abacavir/lamivudine. METHOD: A retrospective cohort study in HIV ...See full text at original site
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引用元:
https://doi.org/10.1016/j.farma.2023.04.007

データ提供:米国国立医学図書館(NLM)

Antiretroviral Therapies and Lipid Profile Changes: Navigating the Desert of HIV Treatment

Antiretroviral therapies (ARTs) have revolutionized the treatment of HIV, transforming a once-deadly disease into a manageable chronic condition. However, like a long and arduous journey through the desert, ARTs can sometimes have unintended side effects. This study explores the potential impact of different ART regimens on lipid profiles, which can influence cardiovascular health. The researchers compared two commonly used ART combinations, seeking to understand their impact on lipid levels and cardiovascular risk.

Comparing ART Regimens: Finding the Best Path for Cardiovascular Health

The study found that one ART regimen, elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide fumarate, was associated with more significant lipid profile changes than the other regimen, dolutegravir/abacavir/lamivudine. This finding is like discovering that one desert path leads to a lush oasis while another leads to a barren wasteland. Understanding these differences is crucial for making informed treatment decisions.

Staying Vigilant: Protecting Cardiovascular Health in the Desert of HIV Treatment

This study highlights the importance of careful monitoring for lipid profile changes during ART treatment. Regular lipid testing can help doctors to identify any potential problems early on, allowing them to adjust treatment strategies and minimize cardiovascular risk. This research is like a skilled guide leading us through the desert of HIV treatment, ensuring that we stay on the path to optimal health.

Dr. Camel's Conclusion

This study, like a well-worn path through the desert of HIV treatment, reminds us of the importance of careful monitoring and personalized care. By understanding the potential impact of different ART regimens on lipid profiles, we can ensure that patients stay on the path to a long and healthy life.

Date :
  1. Date Completed 2023-11-02
  2. Date Revised 2023-11-02
Further Info :

Pubmed ID

37349200

DOI: Digital Object Identifier

10.1016/j.farma.2023.04.007

Related Literature

SNS
PICO Info
in preparation
Languages

English

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