The pyridazine heterocycle in molecular recognition and drug discovery.

Author: MeanwellNicholas A

Paper Details 
Original Abstract of the Article :
The pyridazine ring is endowed with unique physicochemical properties, characterized by weak basicity, a high dipole moment that subtends π-π stacking interactions and robust, dual hydrogen-bonding capacity that can be of importance in drug-target interactions. These properties contribute ...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10015555/

データ提供:米国国立医学図書館(NLM)

The Pyridazine Ring: A Powerful Tool for Drug Discovery

In the vast desert of drug discovery, researchers are constantly searching for new compounds with unique properties. This study focuses on the pyridazine ring, a specific chemical structure that's proving to be quite valuable in drug development. It has some special characteristics, like its ability to form strong bonds with other molecules, making it a promising candidate for designing new medications. The study highlights the potential of pyridazine in various applications, particularly in addressing challenges related to drug optimization.

A Versatile Chemical Structure with Potential

The pyridazine ring is a versatile player in the world of drug discovery. It's not only unique in its ability to form strong bonds with other molecules, but also in its ability to reduce side effects. The study shows how pyridazine is already being used in FDA-approved drugs and its potential to be used in even more medications in the future.

Pyridazine: A Promising Future

The study emphasizes the importance of exploring and understanding different chemical structures like the pyridazine ring. This could be a key to unlocking new and more effective treatments for a wide range of diseases.

Dr.Camel's Conclusion

Just as a camel adapts to the harsh desert environment, the pyridazine ring is adaptable and versatile. It's a promising new tool in the fight against disease, showing that even in the vast expanse of drug discovery, hidden gems can be found.

Date :
  1. Date Completed n.d.
  2. Date Revised 2023-09-28
Further Info :

Pubmed ID

37362319

DOI: Digital Object Identifier

PMC10015555

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Languages

English

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