Effects of Lenvatinib on Skeletal Muscle Volume and Cardiac Function in Patients with Hepatocellular Carcinoma.

Author: AmanumaMakoto, DaidoYasuko, HigaiKoji, IgarashiYoshinori, KobayashiKojiro, MatsudaTakahisa, MatsuiTeppei, MatsukiyoYasushi, MohriKunihide, MomiyamaKoichi, MukozuTakanori, NagaiHidenari, NagumoHideki, OginoYu, WakuiNoritaka, WatanabeGo, YoshimineNaoyuki

Paper Details 
Original Abstract of the Article :
Previously, we reported that the tyrosine kinase inhibitor (TKI) sorafenib decreases serum levels of carnitine and reduces skeletal muscle volume. Moreover, others reported that TKIs might lead to cardiomyopathy or heart failure. Therefore, this study aimed to evaluate the effects of lenvatinib (LEN...See full text at original site
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引用元:
https://doi.org/10.1159/000531562

データ提供:米国国立医学図書館(NLM)

Lenvatinib: Investigating the Impact on Muscle and Cardiac Function

The complex landscape of cancer treatment is often likened to navigating a desert, where each treatment option has its own set of potential benefits and risks. This research investigates the impact of lenvatinib (LEN), a tyrosine kinase inhibitor (TKI), on skeletal muscle volume and cardiac function in patients with hepatocellular carcinoma (HCC). The study explores the potential for LEN to affect muscle mass and cardiac health, building upon previous research that suggested potential adverse effects of TKIs on these systems. This research provides valuable insights into the potential side effects of LEN, highlighting the importance of careful monitoring and management for patients receiving this treatment.

Lenvatinib: A Desert Oasis of Hope with Potential Side Effects

This research underscores the importance of carefully monitoring patients receiving LEN for potential effects on skeletal muscle volume and cardiac function. While LEN offers a promising treatment option for HCC, the study suggests the need for vigilance regarding potential adverse effects. This research encourages clinicians to be aware of the potential for LEN to impact muscle mass and cardiac health, allowing them to adjust treatment plans and provide appropriate interventions to mitigate any negative effects. This research serves as a reminder that even effective cancer treatments may come with potential side effects, and it emphasizes the importance of a comprehensive approach to patient care that balances therapeutic benefits with potential risks.

Navigating Cancer Treatment: A Desert Oasis of Knowledge and Support

Just as a desert traveler needs a reliable guide and access to vital resources, patients with cancer require a knowledgeable healthcare team and a supportive network. This research highlights the importance of ongoing research and monitoring of cancer treatment options to ensure their safety and effectiveness. It encourages individuals undergoing cancer treatment to communicate openly with their healthcare providers about any concerns they may have, ensuring that they receive the best possible care and support throughout their journey.

Dr.Camel's Conclusion

This study underscores the importance of carefully evaluating the potential side effects of cancer treatments, even those that offer promising therapeutic benefits. The research highlights the need for ongoing research to better understand the impact of LEN on skeletal muscle volume and cardiac function, ensuring that patients receive safe and effective treatment. This research emphasizes the importance of a comprehensive approach to cancer care, balancing therapeutic benefits with potential risks and providing comprehensive support to patients throughout their treatment journey.

Date :
  1. Date Completed 2023-10-04
  2. Date Revised 2023-10-04
Further Info :

Pubmed ID

37364546

DOI: Digital Object Identifier

10.1159/000531562

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Languages

English

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