Effects of pseudoephedrine on rat fetal bone development: evaluation by three different methods.

Author: BalcıoğluEsra, CeylanTayfun, DeğermenciMuhammet, UnurErdoğan, Uçarİlyas, YiğitHüseyin, ÖnderGözde Özge

Paper Details 
Original Abstract of the Article :
Pseudoephedrine (PSE) is an agent that is contained in common cold medications. The agent, which is used to treat cold and cough, is the fourth most prescribed drug group in some countries. During pregnancy, expectant mothers use PSE for colds and other reasons. One out of every four expectant mothe...See full text at original site
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引用元:
https://doi.org/10.1007/s12565-023-00733-7

データ提供:米国国立医学図書館(NLM)

Pseudoephedrine: A Potential Threat to Fetal Bone Development

Pseudoephedrine (PSE), a common ingredient in cold medications, is widely used to alleviate cold and cough symptoms. However, its potential impact on fetal development, particularly bone formation, remains a concern. This study investigates the effects of PSE on fetal long bone development in rats. Pregnant rats were administered different doses of PSE throughout their pregnancy, and the fetal long bones were analyzed. The results showed that PSE significantly decreased fetal bone length, ossification rate, and calcium content. These findings suggest that PSE may have detrimental effects on fetal bone development, highlighting the importance of careful consideration of PSE use during pregnancy.

PSE: A Potential Risk for Fetal Bone Development

The study revealed that PSE can significantly impact fetal bone development, potentially affecting bone length, ossification, and calcium content. This highlights the importance of cautious use of PSE during pregnancy, particularly for expectant mothers concerned about fetal health and development. Further research is needed to understand the specific mechanisms involved and the potential long-term consequences of PSE exposure during pregnancy.

PSE: A Reminder of Potential Risks in Pregnancy

Pregnancy is a critical period for fetal development, and careful consideration of medication use is essential. This study highlights the potential risks of PSE exposure during pregnancy, emphasizing the importance of consulting with healthcare professionals regarding the safe use of medications during this time. Pregnant women should prioritize their health and the well-being of their developing child by making informed decisions about medication use.

Dr. Camel's Conclusion

Just as a camel's strong bones are crucial for navigating the harsh desert environment, proper bone development is critical for a fetus. This study sheds light on the potential risks of PSE exposure during pregnancy, suggesting that PSE may impede fetal bone development. This underscores the importance of informed decisions regarding medication use during pregnancy, prioritizing the health and well-being of both mother and child.

Date :
  1. Date Completed n.d.
  2. Date Revised 2023-06-30
Further Info :

Pubmed ID

37389734

DOI: Digital Object Identifier

10.1007/s12565-023-00733-7

Related Literature

SNS
PICO Info
in preparation
Languages

English

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