Paper Details 
Original Abstract of the Article :
Epilepsy is one of the major neuron-damaging neurological disorders. Generalized tonic-clonic seizure (GTCS) is the commonest one. Refractory patterns cannot be controlled by simple monotherapy with antiepileptic drugs (AEDs). Valproic acid (VPA) is one of the widely prescribed AEDs but it may not c...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312407/

データ提供:米国国立医学図書館(NLM)

Clobazam as an Add-on Drug for Refractory Generalized Tonic-Clonic Seizures

This study explores the challenging realm of epilepsy management, focusing on the treatment of generalized tonic-clonic seizures (GTCS), a common type of seizure that can significantly impact individuals' lives. The researchers investigate the effectiveness and safety of clobazam as an add-on drug in patients with refractory GTCS, meaning seizures that are not adequately controlled with valproic acid monotherapy.

Improving Seizure Control with Clobazam

The study suggests that clobazam, when used as an add-on drug in patients with refractory GTCS, can effectively improve seizure control. The researchers highlight the potential of clobazam to enhance the efficacy of valproic acid, a commonly prescribed antiepileptic drug, in managing challenging seizure patterns. This research offers potential for improved seizure control and improved quality of life for individuals with refractory GTCS.

A New Path Through the Desert of Epilepsy

This research provides valuable insights into the management of refractory GTCS, a condition that can significantly impact individuals' lives. The study suggests that clobazam, when used as an add-on drug, can be a valuable tool for improving seizure control and reducing the burden of epilepsy. It's like discovering a new path through the vast and often challenging desert of epilepsy, offering hope for a brighter future for those struggling with this condition.

Dr.Camel's Conclusion

This study highlights the potential of clobazam as an effective add-on drug for managing refractory GTCS. The research suggests that clobazam can improve seizure control and quality of life for individuals with this challenging condition. It's like finding a refreshing oasis in the vast desert of epilepsy, providing hope for a brighter future for those affected.

Date :
  1. Date Completed n.d.
  2. Date Revised 2023-07-04
Further Info :

Pubmed ID

37397124

DOI: Digital Object Identifier

PMC10312407

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.