Experience With Elexacaftor/Tezacaftor/Ivacaftor in Patients With Cystic Fibrosis and Advanced Disease.

Author: Asensio de la CruzÓscar, Balaguer CartagenaMari Nieves, Blanco AparicioMarina, Blitz CastroEnrique, Carrasco HernándezLaura, Delgado PecellínIsabel, Diab-CáceresLaila, Expósito MarreroAndrea, Felipe MontielAlmudena, García ClementeMarta, Girón MorenoRosa Mª, Gómez BonillaAinhoa, Gómez CrespoBeatriz, Luna ParedesCarmen, López NeyraAlejandro, OlveiraCasilda, OlveiraGabriel, PeláezAdrián, Prados SanchezConcha, Quaresma VázquezJoana, Quintana GallegoEsther, Ramos HernándezCristina, Rodríguez GonzálezJesús, Sanz SantiagoVerónica, SoleAmparo, Solís GarcíaMarta, Zamarrón de LucasEster, Álvarez FernándezAntonio

Paper Details 
Original Abstract of the Article :
INTRODUCTION: Elexacaftor/tezacaftor/ivacaftor (ETI) was used through the early access programme in Spain from December 2019 in cystic fibrosis (CF) patients with homozygous or heterozygous F508del mutation with advanced lung disease. METHODOLOGY: Multicentre, ambispective, observational, study in ...See full text at original site
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引用元:
https://doi.org/10.1016/j.arbres.2023.05.017

データ提供:米国国立医学図書館(NLM)

Elexacaftor/Tezacaftor/Ivacaftor: A New Oasis in the Desert of Cystic Fibrosis

The journey of individuals with [cystic fibrosis (CF)] is often marked by challenges, much like a caravan traversing a harsh desert. This study, like a team of researchers mapping out a new path through the desert, investigates the potential benefits of [elexacaftor/tezacaftor/ivacaftor (ETI)] in patients with CF and advanced lung disease. The research explores the drug's efficacy in improving lung function, reducing exacerbations, and enhancing overall quality of life.

A Promising Oasis: ETI's Potential to Improve Cystic Fibrosis Outcomes

This research, like a caravan discovering a hidden oasis in a vast desert, offers promising results for individuals with [cystic fibrosis]. The findings indicate that [ETI] may be a valuable treatment option, potentially improving [lung function, reducing exacerbations, and enhancing overall quality of life]. This discovery, like a hidden well in the desert, could lead to significant improvements in the lives of people with CF.

Navigating the Landscape: A Multi-faceted Approach to CF Treatment

This research, like a map guiding a caravan through a complex and challenging landscape, highlights the need for a multi-faceted approach to [cystic fibrosis] treatment. The findings demonstrate the potential of [ETI] to improve multiple aspects of CF, including [lung function, nutrition, and overall quality of life]. This comprehensive approach, much like a caravan relying on multiple strategies to navigate a desert, is crucial for optimizing treatment outcomes and improving the well-being of individuals with CF.

Dr.Camel's Conclusion

The research on elexacaftor/tezacaftor/ivacaftor for cystic fibrosis offers a glimmer of hope, like a beacon in the desert night. This study suggests that this treatment might be a valuable new tool for managing CF, potentially improving lung function, reducing exacerbations, and enhancing overall quality of life. While further research is needed to fully understand its long-term implications, this research offers a potential new path for individuals with CF, much like a caravan discovering a new route through a vast and challenging desert.

Date :
  1. Date Completed 2023-09-05
  2. Date Revised 2023-09-05
Further Info :

Pubmed ID

37400317

DOI: Digital Object Identifier

10.1016/j.arbres.2023.05.017

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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