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High Efficacy and Safety of Asciminib in a Chronic Myeloid Leukemia Patient with Chronic Kidney Disease Following Renal Transplantation: A Case Report.
Author: AsanoNaomi, EndoMamiko, FukatsuMasahiko, HayashiKiyohito, IkezoeTakayuki, KimuraSatoshi, KoyamaDaisuke, ManabeKazuya, SanoTakahiro, SuzukiKengo, TakahashiHiroshi, TakanoMotoki, UchidaYasuhiro
Original Abstract of the Article :
Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm driven by the BCR::ABL1 tyrosine kinase. Tyrosine kinase inhibitors (TKIs) have been established as standard therapies for CML. However, some CML patients experience TKI intolerance. Asciminib was approved for CML patients either intole...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.2169/internalmedicine.2179-23
データ提供:米国国立医学図書館(NLM)
Asciminib: A Potential Treatment for CML in Patients with Kidney Disease
This case report presents a promising case of asciminib, a tyrosine kinase inhibitor, being used to treat a chronic myeloid leukemia (CML) patient who had undergone a renal transplant and experienced intolerance to other tyrosine kinase inhibitors (TKIs). The researchers highlight the potential of asciminib as a safe and effective treatment option for CML patients with chronic kidney disease.Asciminib: A Safe and Effective Treatment Option
The case report demonstrates the successful use of asciminib in a CML patient with chronic kidney disease who had experienced intolerance to other TKIs. The patient achieved a deep molecular response without any exacerbation of their renal function, suggesting that asciminib may be a viable treatment option for CML patients with kidney disease.Navigating the Desert of Chronic Illness
As a camel, I've learned to adapt to the harsh conditions of the desert, finding ways to thrive even in challenging environments. Chronic illnesses, like CML and chronic kidney disease, can be similarly demanding, requiring ongoing management and treatment. This case report offers a glimmer of hope, suggesting that asciminib may provide a safe and effective treatment option for patients facing these complex medical challenges.Dr.Camel's Conclusion
This case report highlights the potential of asciminib as a safe and effective treatment option for CML patients with chronic kidney disease. The study demonstrates the successful use of asciminib in a patient who had experienced intolerance to other TKIs, suggesting that asciminib may be a valuable addition to the therapeutic arsenal for CML patients with kidney disease. Further research is needed to confirm the safety and efficacy of asciminib in a larger population of CML patients with chronic kidney disease.Date :
- Date Completed n.d.
- Date Revised 2023-07-05
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