Recent advances in the discovery of tropomyosin receptor kinases TRKs inhibitors: A mini review.

Author: Al-QadhiMustafa A, El-NassanHala B

Paper Details 
Original Abstract of the Article :
The tropomyosin receptor tyrosine kinases (TRKs) control the cell proliferation mainly in the nervous system and are encoded by NTRK genes. Fusion and mutation of NTRK genes were detected in various types of cancers. Many small molecules TRK inhibitors have been discovered during the last two decade...See full text at original site
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引用元:
https://doi.org/10.1016/j.ejmech.2023.115618

データ提供:米国国立医学図書館(NLM)

TRK Inhibitors: A New Weapon in the War on Cancer

The fight against cancer is a never-ending journey, like a caravan crossing a vast desert, always seeking new ways to overcome the challenges. This research focuses on TRK inhibitors, a new class of drugs that target a specific protein involved in cancer growth. The researchers reviewed recent advances in the development of these inhibitors, highlighting the progress made in creating more potent and selective drugs. They noted that some of these inhibitors have already been approved for treating certain types of cancer, giving hope for new treatments. However, they also acknowledged the need for continued research to overcome drug resistance and minimize side effects. This research is like a guidebook, leading us through the evolving landscape of cancer treatments.

TRK Inhibitors: A Promising New Direction in Cancer Treatment

This research shines a light on the promising potential of TRK inhibitors in the fight against cancer. The researchers emphasized the need for continued research to refine these drugs and address challenges like drug resistance. It's like finding a new oasis in the desert of cancer treatment, offering hope for patients who have struggled to find effective therapies. This research is a testament to the relentless efforts of scientists to develop new treatments and improve the lives of cancer patients.

Navigating the Future of Cancer Treatment

This research, like a compass guiding us through the desert of cancer, provides valuable insights into the potential of TRK inhibitors. It encourages continued research to develop more effective and targeted treatments, while also addressing the challenges of drug resistance and side effects. This research highlights the importance of ongoing innovation and collaboration in the fight against cancer, reminding us that the journey is long and requires persistent effort.

Dr.Camel's Conclusion

This study, like a caravan carrying hope through the desert of cancer treatment, highlights the potential of TRK inhibitors. It is a testament to the enduring human spirit, forever seeking new solutions to the challenges of disease.

Date :
  1. Date Completed 2023-07-19
  2. Date Revised 2023-07-19
Further Info :

Pubmed ID

37413881

DOI: Digital Object Identifier

10.1016/j.ejmech.2023.115618

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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