Paper Details

  1. Home
  2. Paper Details

Probiotic supplementation during antibiotic treatment is unjustified in maintaining the gut microbiome diversity: a systematic review and meta-analysis.

Author: BarnaViktória, BunducStefania, DemeterDóra, ErőssBálint, Földvári-NagyLászló, HegyiPéter, LentiKatalin, PatoniCristina, VeresDániel Sándor, ÉliásAnna Júlia

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This meta-analysis investigated the effects of probiotic supplementation on gut microbiome composition during antibiotic therapy. It found no significant difference in gut microbiome diversity indices between probiotic supplemented and control groups. While taxonomic composition varied across studies, both groups showed a potential tendency to restore baseline levels after 3-8 weeks. The limited number of studies and low sample sizes are limitations.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Probiotics are often used to prevent antibiotic-induced low-diversity dysbiosis, however their effect is not yet sufficiently summarized in this regard. We aimed to investigate the effects of concurrent probiotic supplementation on gut microbiome composition during antibiotic therapy. M...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10355080/

データ提供：米国国立医学図書館（NLM）

Probiotics and Antibiotics: A Balancing Act in the Desert of Gut Health

The gut microbiome is a complex and dynamic ecosystem, like a vast and ever-shifting desert. This study delves into the delicate balance of the gut microbiome, exploring the impact of antibiotics and probiotics on its diversity. The researchers are like skilled desert ecologists, carefully observing the interactions between different species and seeking to maintain a healthy and thriving ecosystem.

The Impact of Antibiotics: Navigating the Shifting Sands

This study examines the effect of antibiotics on gut microbiome diversity, acknowledging their potential to disrupt the delicate balance of this ecosystem, like a sudden sandstorm that can reshape the landscape. The researchers are exploring the potential of probiotics to mitigate the negative effects of antibiotics, hoping to restore balance and promote a healthy gut microbiome.

A Complex Ecosystem: Seeking Balance in the Gut

This study highlights the intricate interplay between antibiotics, probiotics, and the gut microbiome, recognizing that each element plays a crucial role in maintaining overall health. The researchers are studying the potential of probiotics to restore gut microbiome diversity after antibiotic treatment, emphasizing the importance of finding a balance between these interventions to promote gut health. It's like seeking harmony between different elements in the desert, recognizing that each element plays a vital role in maintaining a balanced and thriving environment.

Dr. Camel's Conclusion

The gut microbiome is a delicate and complex ecosystem, like a vast and ever-shifting desert. This research provides valuable insights into the impact of antibiotics and probiotics on gut microbiome diversity, highlighting the importance of finding a balance between these interventions to maintain a healthy and thriving ecosystem. It's a reminder that even in the face of seemingly insurmountable challenges, there is always hope for a better tomorrow. It's like discovering a hidden oasis in the desert, a source of healing and hope that can sustain us on our journey.

Date :
  1. Date Completed 2023-07-21
  2. Date Revised 2023-07-22
Further Info :

Pubmed ID

37468916

DOI: Digital Object Identifier

PMC10355080

Related Literature

Article Analysis
・Effective treatment of probiotics
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.