Efficacy and tolerability of immediate switch from sodium channel blockers to Lacosamide.

Author: BuluşEser, DumanArda, GürsesCandan, Kandemir YılmazMelek, Keskin GülerSelda, Mert AtmacaMurat, Talha ÖzgünOrhan, ÇelebiÖzlem

Paper Details 
Original Abstract of the Article :
Lacosamide (LCM) is a new-generation anti-seizure medication approved for monotherapy and add-on therapy for focal-onset epilepsy. It has novel pharmacodynamics and favorable pharmacokinetic qualities with good clinical response. This study aims to evaluate the effectiveness and tolerability of LCM ...See full text at original site
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引用元:
https://doi.org/10.1016/j.yebeh.2023.109355

データ提供:米国国立医学図書館(NLM)

Switching to Lacosamide: A New Approach for Epilepsy Management

Epilepsy is a neurological disorder characterized by recurrent seizures. This research examines the efficacy and tolerability of Lacosamide (LCM), a new-generation anti-seizure medication, when used as a direct replacement for sodium channel blockers in patients with focal-onset and generalized-onset epilepsies. The study involved a retrospective analysis of clinical data from patients who switched to LCM, providing insights into the effectiveness and safety of this approach. The authors found that immediate switching to LCM resulted in favorable outcomes, including a significant reduction in seizure frequency, high retention rates, and acceptable adverse effect profiles.

Lacosamide: A Promising Option for Epilepsy Treatment

This study demonstrates the potential benefits of switching to Lacosamide for patients with epilepsy. The authors found that LCM significantly reduced seizure frequency and had a high retention rate, indicating its effectiveness and tolerability. These findings suggest that LCM could be a valuable option for managing epilepsy, particularly when patients experience difficulties with sodium channel blockers.

A New Path for Epilepsy Treatment

This study highlights the importance of exploring new and innovative treatments for epilepsy. Lacosamide represents a potential breakthrough, offering patients a new path to seizure control with favorable outcomes. It's like discovering a hidden oasis in the desert of epilepsy treatments—a haven of relief and hope for patients.

Dr.Camel's Conclusion

This research is a beacon of hope for patients with epilepsy. It demonstrates the potential of Lacosamide as a new and effective treatment option. It's like finding a cool spring in the desert, offering a refreshing change for those seeking relief from seizures.

Date :
  1. Date Completed 2023-08-07
  2. Date Revised 2023-08-08
Further Info :

Pubmed ID

37473655

DOI: Digital Object Identifier

10.1016/j.yebeh.2023.109355

Related Literature

SNS
PICO Info
in preparation
Languages

English

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