[Impact of voxelotor on hemoglobin electrophoretic and chromatographic profiles].

Author: BastardJean-Philippe, FellahiSoraya, GalacterosFrédéric, GiraudBaptiste, JolyPhilippe, MartinoSuella, MouriNadir, MoutereauStéphane, SakkaMehdi, de LunaGonzalo

Paper Details 
Original Abstract of the Article :
Voxelotor (GBT440, OXBRYTA®) appeared recently as one of the possible treatments for sickle cell disease. This molecule, by binding the alpha globin of hemoglobin, causes hyperaffinity of the latter for oxygen and reduces its polymerization properties. Several therapeutic trials have been able to sh...See full text at original site
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引用元:
https://doi.org/10.1684/abc.2023.1814

データ提供:米国国立医学図書館(NLM)

Unlocking the Mystery of Voxelotor: A New Approach to Sickle Cell Disease

Sickle cell disease, a genetic condition affecting red blood cells, is a challenging illness, often leading to chronic pain, fatigue, and organ damage. It's like navigating a desert with a faulty compass, constantly facing challenges and uncertainties. Voxelotor, a new drug, offers a potential solution by binding to hemoglobin and altering its properties, making it more effective at carrying oxygen. This study explores the impact of voxelotor on hemoglobin profiles, highlighting its potential to revolutionize the treatment of sickle cell disease.

Navigating the Sickle Cell Desert with a New Compass

The study suggests that voxelotor has a distinct impact on hemoglobin profiles, offering new insights into its mechanism of action. This research provides valuable information for healthcare professionals monitoring patients treated with voxelotor, helping them navigate the complexities of this condition.

Hope on the Horizon: Voxelotor's Impact on Sickle Cell Disease

Voxelotor's potential to improve the lives of individuals with sickle cell disease is exciting. This research offers a glimpse of hope, as it illuminates a new path for managing this challenging condition and alleviating the burdens it poses. It's like finding a hidden oasis in the desert, providing respite and a sense of optimism.

Dr.Camel's Conclusion

The journey to find effective treatments for sickle cell disease is ongoing. Voxelotor, with its unique mechanism of action, offers a promising new direction for managing this complex condition. This research provides valuable information for healthcare professionals and researchers, helping us navigate the complexities of sickle cell disease and provide better care for those affected.
Date :
  1. Date Completed 2023-07-24
  2. Date Revised 2023-07-24
Further Info :

Pubmed ID

37475172

DOI: Digital Object Identifier

10.1684/abc.2023.1814

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Languages

French

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