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Serum potassium response to single-dose sodium zirconium cyclosilicate for the treatment of asymptomatic hyperkalemia in hospitalized patients.

Author: LewisHaley, StamperBenton, YungkurthAlyssa Claudio

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Single-dose sodium zirconium cyclosilicate (SZC) was more effective than three doses of SZC in managing asymptomatic hyperkalemia in hospitalized patients. However, single-dose SPS was more effective than single-dose SZC. Single-dose SZC may be a suitable option for managing asymptomatic hyperkalemia, but patients with higher baseline potassium levels and impaired renal function may require alternative treatments.
Paper Details　
Original Abstract of the Article :
STUDY OBJECTIVE: To assess the efficacy of single-dose sodium zirconium cyclosilicate (SZC) compared to the FDA approved three times daily (TID) dosing and to single-dose sodium polystyrene sulfonate (SPS) for the management of asymptomatic hyperkalemia in hospitalized patients. DESIGN: Single-cent...See full text at original site
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引用元：
https://doi.org/10.1002/phar.2854

データ提供：米国国立医学図書館（NLM）

Sodium Zirconium Cyclosilicate: A New Approach to Asymptomatic Hyperkalemia

Hyperkalemia, an imbalance in potassium levels, can be a silent threat, like a mirage in the desert that appears harmless but can lead to complications. This study investigates the efficacy of sodium zirconium cyclosilicate (SZC) in managing asymptomatic hyperkalemia in hospitalized patients.

Sodium Zirconium Cyclosilicate: A Promising Treatment for Asymptomatic Hyperkalemia

The study found that single-dose SZC was effective in achieving normokalemia in a significant proportion of patients. However, achieving normokalemia with one dose was less likely in individuals with higher baseline potassium levels and impaired renal function.

Navigating the Sands of Hyperkalemia: A Safe and Effective Treatment

This study provides valuable insight into the management of asymptomatic hyperkalemia in hospitalized patients.

Dr.Camel's Conclusion

Hyperkalemia, like a looming sandstorm, requires careful management. This study highlights the potential of sodium zirconium cyclosilicate as a safe and effective treatment option, particularly in patients with asymptomatic hyperkalemia.

Date :
  1. Date Completed n.d.
  2. Date Revised 2023-07-28
Further Info :

Pubmed ID

37475499

DOI: Digital Object Identifier

10.1002/phar.2854

Related Literature

Article Analysis
・Effects of sodium polystyrene sulfonate
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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