Paper Details 
Original Abstract of the Article :
Real-world US healthcare resource utilization (HRU) and costs during first salvage therapy for relapsed/refractory (R/R) acute myeloid leukemia (AML) are described using IBM MarketScan® data (1/1/2007-6/30/2020). Treatments included high- (HIC) and low-intensity chemotherapy (LIC) alone, and gi...See full text at original site
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引用元:
https://doi.org/10.1080/10428194.2023.2235044

データ提供:米国国立医学図書館(NLM)

Navigating the Healthcare Landscape of Relapsed/Refractory AML: A Real-World Perspective

Relapsed/refractory (R/R) acute myeloid leukemia (AML) is a challenging condition with significant healthcare resource utilization and costs. This research provides a real-world perspective on healthcare resource utilization (HRU) and costs associated with first salvage therapy for R/R AML in the United States. The researchers analyzed data from the IBM MarketScan database to understand the HRU and costs associated with various treatment regimens, including high- and low-intensity chemotherapy, as well as targeted therapies like gilteritinib, other FLT3 tyrosine kinase inhibitors (TKIs), and venetoclax.

A Complex Landscape: Understanding the Costs of R/R AML Treatment

The study revealed substantial variations in HRU and costs across different treatment approaches for R/R AML. High-intensity chemotherapy, while requiring more inpatient care, resulted in higher overall costs compared to other treatments. Targeted therapies, such as venetoclax, exhibited a moderate level of HRU and costs. This research provides valuable insights into the economic burden of R/R AML treatment, highlighting the need for cost-effective and personalized treatment strategies.

Optimizing Treatment Strategies: A Collaborative Effort for R/R AML

The findings underscore the importance of a collaborative approach to managing R/R AML, considering both clinical effectiveness and cost-effectiveness. By understanding the diverse HRU and costs associated with different treatment options, healthcare professionals can work with patients to develop personalized treatment plans that balance clinical goals with economic realities. This study serves as a valuable tool for navigating the complexities of R/R AML treatment and optimizing patient care.

Dr.Camel's Conclusion

This research provides a valuable real-world perspective on the healthcare resource utilization and costs associated with first salvage therapy for relapsed/refractory acute myeloid leukemia (R/R AML). The study highlights the substantial variations in HRU and costs across different treatment approaches, emphasizing the importance of a collaborative approach to managing R/R AML, considering both clinical effectiveness and cost-effectiveness. It's a reminder that the desert of healthcare is a complex and challenging landscape, and that navigating this landscape requires a careful understanding of the resources available, the costs associated with treatment, and the individual needs of each patient.

Date :
  1. Date Completed 2023-11-07
  2. Date Revised 2023-11-07
Further Info :

Pubmed ID

37486091

DOI: Digital Object Identifier

10.1080/10428194.2023.2235044

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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