Paper Details

  1. Home
  2. Paper Details

The nutritional impact of CD19-targeted CAR-T therapy versus BEAM chemotherapy for adult patients with lymphoma.

Author: AhernKatie, Correia De FariasMadson, PhamJames, SandersonRobin, WalshKevin

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study investigated the impact of CAR-T cell therapy on nutritional status in patients with lymphoma compared to a conditioning regimen for autologous haematopoetic stem cell transplant (BEAM). The study aimed to determine the prevalence of nutrition impact symptoms (NIS) and nutritional status within 30 days post-treatment.
Paper Details　
Original Abstract of the Article :
Chimeric antigen receptor T (CAR-T) cell therapy is a novel therapy demonstrating durable remissions in patients with refractory or relapsing non-Hodgkin's B-cell lymphoma. Maintaining a patient's nutritional status has been demonstrated to improve outcomes in cancer treatment. However, no studies h...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1111/jhn.13210

データ提供：米国国立医学図書館（NLM）

Nutritional Impact of CAR-T Therapy and BEAM Chemotherapy in Lymphoma Patients

Chimeric antigen receptor T (CAR-T) cell therapy has revolutionized treatment for lymphoma, offering a beacon of hope in the desert of challenging cancers. This study investigates the nutritional impact of CAR-T therapy compared to BEAM chemotherapy, a standard conditioning regimen for autologous hematopoietic stem cell transplant (HSCT), in patients with lymphoma. The study aimed to determine the prevalence of nutrition impact symptoms (NIS) and nutritional status within 30 days post-treatment.

CAR-T Therapy: Navigating the Nutritional Landscape

The study found that CAR-T therapy, despite its remarkable therapeutic potential, may have a more favorable impact on nutritional status than BEAM chemotherapy. This finding highlights the importance of considering the nutritional needs of patients undergoing CAR-T therapy and optimizing their care to ensure optimal outcomes.

Maintaining Nutrition: A Vital Aspect of Cancer Care

This study reinforces the importance of nutritional management in cancer treatment. The study suggests that CAR-T therapy may have a less detrimental impact on nutritional status compared to BEAM chemotherapy, highlighting the need for individualized nutritional care plans for patients undergoing these treatments. This is crucial for supporting their overall health and well-being during the recovery process.

Dr.Camel's Conclusion

This study provides valuable insights into the nutritional considerations for patients undergoing CAR-T therapy and BEAM chemotherapy. The findings emphasize the importance of individualized care and monitoring to ensure optimal nutritional status, which is essential for supporting patient recovery and maximizing the benefits of these treatments. It's like providing a nourishing oasis for patients navigating the challenges of cancer treatment.

Date :
  1. Date Completed 2023-09-27
  2. Date Revised 2023-09-27
Further Info :

Pubmed ID

37489541

DOI: Digital Object Identifier

10.1111/jhn.13210

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.