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Comparative assessment of efficacy and safety of approved oral therapies for overactive bladder: a systematic review and network meta-analysis.

Author: CuiWenyan, HeWenjuan, HuangGuangliang, LiDan, LiuXiuju, SunQian, TianYunfei, ZhaoXiaojuan, ZhaoYonghong

Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Solifenacin showed the best efficacy for overactive bladder. Most anticholinergic drugs were more likely to cause dry mouth and constipation, with lower doses being better tolerated. The choice of drugs should be tailored to the patient's specific situation.
Paper Details　
Original Abstract of the Article :
UNLABELLED: bladder based on a systematic review and network meta-analysis approach. METHODS: Pubmed, Embase, Web of Science, and the Cochrane Register of Clinical Trials databases were systematically searched. The search time frame was from database creation to June 2, 2022. Randomized controlled ...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482468/

データ提供：米国国立医学図書館（NLM）

Overactive Bladder: A Comprehensive Guide to Treatment Options

Overactive bladder (OAB) is a common condition that can significantly impact quality of life. This research provides a comprehensive overview of the efficacy and safety of approved oral therapies for OAB, analyzing data from multiple clinical trials. The researchers employed a systematic review and network meta-analysis approach to compare the effectiveness and side effects of various OAB medications, offering valuable insights for healthcare professionals and patients.

Navigating the Desert of OAB: Choosing the Right Treatment

The study found that solifenacin emerged as the most effective medication for managing OAB symptoms, particularly in terms of reducing the frequency of urination and incontinence episodes. This is like finding the most effective water source in a vast desert, providing optimal hydration and relief. The researchers meticulously compared the efficacy and safety of various OAB medications, offering a comprehensive guide for clinicians and patients to navigate the treatment options.

A Desert Oasis of Knowledge: Understanding Treatment Options

This research provides a valuable resource for individuals seeking information about OAB treatment. It offers a comprehensive overview of the various oral therapies available, their effectiveness, and their potential side effects. This knowledge empowers patients to have informed conversations with their healthcare providers, making informed decisions about their treatment plan.

Dr.Camel's Conclusion

This research is like a map guiding us through the desert of OAB treatment options. It provides a comprehensive analysis of the available therapies, helping us navigate the complexities of managing this condition. By understanding the efficacy and safety of various medications, patients and healthcare professionals can make informed decisions to achieve the best possible outcomes.
Date :
  1. Date Completed 2023-11-02
  2. Date Revised 2023-11-08
Further Info :

Pubmed ID

37506033

DOI: Digital Object Identifier

PMC10482468

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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