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Daridorexant as a novel pharmacotherapeutic approach in insomnia: a systematic review and meta-analysis.

Author: CharanJaykaran, DhingraSameer, DuttaSiddhartha, HaqueMainul, ShahRima, SinghalShubha

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Daridorexant was a safer and efficacious agent for induction and maintenance of sleep for chronic insomnia. This conclusion was drawn from a meta-analysis of four RCTs evaluating the efficacy and safety of daridorexant for insomnia. Daridorexant was associated with a reduced risk of treatment-emergent adverse events compared to placebo.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Insomnia is a multi-factorial disorder with conventional treatment options that are not satisfactory for many patients. This metaanalysis analyzed the safety and efficacy of daridorexant. METHODS: An electronic database search for RCTs was conducted on Medline via PubMed, Cochrane, and ...See full text at original site
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引用元：
https://doi.org/10.1080/14740338.2023.2243217

データ提供：米国国立医学図書館（NLM）

Daridorexant: A New Oasis in the Desert of Insomnia

Insomnia, that relentless desert of sleeplessness, affects millions. This meta-analysis examines the efficacy and safety of daridorexant, a novel drug that promises to bring relief. The authors conducted a systematic review of randomized controlled trials (RCTs) to assess daridorexant's impact on sleep induction and maintenance. They found that daridorexant, particularly at a dose of 25 mg, was effective in improving sleep quality, with a favorable safety profile compared to placebo. This suggests that daridorexant could be a valuable addition to the therapeutic arsenal for chronic insomnia, offering hope for a more peaceful night's rest.

Daridorexant: A Potential Solution for Chronic Insomnia

This meta-analysis demonstrates that daridorexant holds promise as an effective and safe treatment for chronic insomnia. It may provide a valuable option for patients who haven't found relief with traditional approaches, offering a potential oasis of restful sleep in the desert of sleeplessness.

A New Dawn for Sleep

This study is a beacon of hope for individuals struggling with chronic insomnia. While more research is needed to fully understand its long-term effects, daridorexant shows promising potential for improving sleep quality and reducing the burden of this common condition.

Dr.Camel's Conclusion

Insomnia can be a challenging desert to navigate, leaving many feeling lost and weary. This meta-analysis offers a promising glimpse of a potential oasis in the form of daridorexant. While further research is needed, this medication holds the potential to transform the lives of those struggling to find restful sleep, paving the way for a brighter and more refreshed tomorrow.
Date :
  1. Date Completed n.d.
  2. Date Revised 2023-10-17
Further Info :

Pubmed ID

37526060

DOI: Digital Object Identifier

10.1080/14740338.2023.2243217

Related Literature

Article Analysis
・Effects of daridorexant
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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