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Formulation and In Vitro Evaluation of a Ramipril Entrapped in a Microsponge-based Drug-delivery System.
Author: AbdulbaqiMustafa R, RahmaniMaha H Philip, SameinLaith Hamza, TaghiHassanien Sagban
Original Abstract of the Article :
Microsponges are porous cross-linked polymers, which have the ability to load a wide range of pharmaceutical active ingredients. They are used topically for long-term treatment applications in addition to the oral route of administration. They are characterized by the efficient distribution of activ...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://pubmed.ncbi.nlm.nih.gov/37595176
データ提供:米国国立医学図書館(NLM)
Microsponges: A Desert Oasis for Drug Delivery
The world of drug delivery is vast and complex, much like an endless desert. Researchers are constantly seeking ways to improve drug delivery systems, aiming for more effective and targeted treatment. This study explores the potential of microsponges as a novel drug-delivery system for ramipril, a drug used to treat high blood pressure. This is like finding a hidden oasis in the desert, offering a potentially more efficient and effective way to deliver medication.
The study aimed to develop a novel drug-delivery system using ramipril-loaded microsponges. The researchers evaluated different formulations of microsponges containing ramipril and Eudragit L 100, exploring the impact of different ratios on the physical characteristics and drug release profile. The study demonstrated the feasibility of incorporating ramipril into microsponge formulations, with the potential to improve drug delivery and reduce side effects. This finding could be like discovering a new and more reliable source of water in the desert, providing a more sustainable and effective way to deliver medication.
A Promise of Better Drug Delivery
The development of ramipril-loaded microsponges could represent a significant advancement in drug delivery, offering a potential alternative to conventional dosage forms. This new approach could potentially improve the therapeutic efficacy of ramipril while minimizing side effects, providing a more targeted and efficient delivery system. This discovery is like finding a new and more efficient method for navigating the vast desert of drug delivery, leading to more effective and tailored treatments for patients.
A Journey Through Drug Delivery
The development of ramipril-loaded microsponges is a promising step in the journey towards more effective and targeted drug delivery. As we continue to explore this new approach, we may find even more innovative and efficient solutions to address the challenges of drug delivery. It's like discovering new pathways through the vast desert of pharmaceutical research, leading to a brighter future for drug development and patient care.
Dr. Camel's Conclusion
The development of ramipril-loaded microsponges offers a promising new avenue for drug delivery, potentially leading to more effective and targeted treatment options. This is like finding a new and more efficient caravan route through the desert, leading to a more sustainable and effective way to deliver life-saving medications.
Date :
- Date Completed 2023-11-02
- Date Revised 2023-11-02
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