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Revisiting six established practices in the treatment of chronic myeloid leukaemia.
Author: JabbourElias, KantarjianHagop M, WelchMary Alma
Original Abstract of the Article :
After two decades of use in chronic myeloid leukaemia, the risks and benefits of established treatment practices for BCR::ABL1 tyrosine kinase inhibitors (TKIs) in the chronic myeloid leukaemia in chronic phase of the disease should be analysed. In this Viewpoint, we suggest that the use of lower th...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1016/S2352-3026(23)00164-3
データ提供:米国国立医学図書館(NLM)
Revisiting Established Practices in Chronic Myeloid Leukemia Treatment: A New Perspective
The landscape of chronic myeloid leukemia (CML) treatment has dramatically evolved. This Viewpoint article revisits established practices related to the use of BCR::ABL1 tyrosine kinase inhibitors (TKIs) in CML, offering a critical analysis of current practices and suggesting potential areas for optimization.
The authors propose that lower TKI doses might be equally effective, potentially leading to reduced side effects and improved treatment compliance. They also suggest that changing TKIs solely based on a lack of early molecular response might not be necessary. Furthermore, they advocate for a more nuanced approach to TKI dose reduction in response to side effects, suggesting that lowering the dose might be preferable to switching TKIs. The article concludes by emphasizing the importance of cost-effectiveness in TKI therapy.
A New Paradigm for Chronic Myeloid Leukemia Management
This Viewpoint article offers a fresh perspective on established practices in CML treatment, suggesting potential adjustments to optimize treatment efficacy, minimize side effects, and improve cost-effectiveness.
A Camel's Perspective on Long-Term Treatment
As a camel, I've witnessed the enduring nature of life in the desert. This Viewpoint article reminds us that long-term treatment strategies require constant reevaluation and adaptation to optimize outcomes and minimize the burden of side effects.
Dr.Camel's Conclusion
This Viewpoint article provides a critical analysis of established practices in the treatment of chronic myeloid leukemia, suggesting potential areas for optimization to improve treatment outcomes, minimize side effects, and enhance cost-effectiveness. The insights presented can guide clinicians in making informed decisions about TKI therapy, ensuring that patients receive the best possible care.
Date :
- Date Completed n.d.
- Date Revised 2023-10-05
Further Info :
Related Literature
English
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