Comparative efficacy and safety of different combinations of three CDK4/6 inhibitors with endocrine therapies in HR+/HER-2 - metastatic or advanced breast cancer patients: a network meta-analysis.

Author: CaiJiehui, ChenLingzhi, ChenYaokun, ChenYexi, JiZeqi, LiZhiyang, LinWeixun, LiuYiyuan, WuJinyao, ZhengDaitian, ZhengJiehua, ZouJuan

Paper Details 
Original Abstract of the Article :
This network meta-analysis aimed to assess the comparative efficacy and safety of combinations involving three cyclin-dependent kinase 4/6 (CDK4/6) inhibitors and endocrine therapies (ETs) in patients with metastatic or advanced breast cancer (BC) who are hormone receptor-positive (HR+) and human ep...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469949/

データ提供:米国国立医学図書館(NLM)

A Comprehensive Look at CDK4/6 Inhibitors in Breast Cancer

This study examines the efficacy and safety of different combinations involving three cyclin-dependent kinase 4/6 (CDK4/6) inhibitors and endocrine therapies (ETs) in patients with metastatic or advanced breast cancer. It's like examining a vast desert landscape, uncovering the effectiveness of various strategies for combatting a challenging disease. The study found that CDK4/6 inhibitors, in combination with ETs, showed varying degrees of efficacy and safety profiles. This study provides valuable insights for clinicians in choosing the most appropriate treatment options for individual patients.

CDK4/6 Inhibitors: A New Weapon in the Fight Against Breast Cancer

This study provides a comprehensive analysis of the use of CDK4/6 inhibitors in breast cancer treatment. It's like mapping out a desert, identifying the most effective routes for navigating this complex disease. The study found that CDK4/6 inhibitors, in combination with ETs, have shown promising results in treating metastatic or advanced breast cancer.

Personalized Breast Cancer Treatment: An Essential Approach

This study emphasizes the importance of personalized medicine in breast cancer treatment. It's a reminder that every patient is unique and requires a tailored approach to optimize treatment outcomes. This study provides a roadmap for clinicians to select the most appropriate combination of therapies for individual patients based on their specific needs.

Dr.Camel's Conclusion

This study is a valuable resource for clinicians navigating the challenging landscape of breast cancer treatment. It emphasizes the importance of personalized medicine and the ongoing search for effective treatments for this complex disease. It's a reminder that just as camels have adapted to the diverse conditions of the desert, we need to be adaptable and innovative in our approach to treating cancer.

Date :
  1. Date Completed 2023-09-04
  2. Date Revised 2023-11-20
Further Info :

Pubmed ID

37653504

DOI: Digital Object Identifier

PMC10469949

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Languages

English

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