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Efficacy and safety of trifluridine/tipiracil plus ramucirumab in comparison with trifluridine/tipiracil monotherapy for patients with advanced gastric cancer-single institutional experience.
Author: KawazoeAkihito, KotaniDaisuke, KubokiYasutoshi, MishimaSaori, NakamuraHitomi, NakamuraYoshiaki, OkunakaMashiro, ShitaraKohei
Original Abstract of the Article :
Trifluridine/tipiracil plus VEGF inhibition with ramucirumab (RAM) for advanced gastric cancer (AGC) demonstrated clinical activity with an acceptable toxicity profile in previous phase II trial. However, little is known about its efficacy and safety in clinical practice in comparison with triflurid...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1007/s10120-023-01427-9
データ提供:米国国立医学図書館(NLM)
Trifluridine/Tipiracil Plus Ramucirumab: A New Oasis in the Desert of Gastric Cancer
Gastric cancer is a formidable disease, often presenting with advanced stages that require aggressive treatment. This study investigated the efficacy and safety of trifluridine/tipiracil plus ramucirumab (RAM) in comparison to trifluridine/tipiracil monotherapy for patients with advanced gastric cancer. The authors sought to evaluate the clinical activity and toxicity profile of this combination therapy.
A New Treatment Landscape for Gastric Cancer: Navigating the Desert of Advanced Disease
The study found that the combination of trifluridine/tipiracil plus ramucirumab demonstrated clinical activity and an acceptable toxicity profile. This finding suggests that this combination therapy may offer a promising new treatment option for patients with advanced gastric cancer, particularly in situations where monotherapy has failed or is not suitable.
Finding Hope in the Desert of Treatment Options
The study underscores the importance of personalized treatment approaches for patients with gastric cancer, considering the unique characteristics of each individual. By exploring new combination therapies and evaluating their efficacy and safety profiles, we can expand the options available for patients and improve their chances of survival and quality of life.
Dr.Camel's Conclusion
The desert of gastric cancer can be a daunting and unforgiving place, but with the development of new therapies like trifluridine/tipiracil plus ramucirumab, we can offer a new oasis of hope for those battling this disease. This study provides valuable insights into the potential of this combination therapy, paving the way for more effective treatment strategies and improved outcomes for patients.
Date :
- Date Completed 2023-11-13
- Date Revised 2023-12-13
Further Info :
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