Targeted Therapy for Cancers: From Ongoing Clinical Trials to FDA-Approved Drugs.

Author: ChangJi-Eun, ChoiHa Yeong

Paper Details 
Original Abstract of the Article :
The development of targeted therapies has revolutionized cancer treatment, offering improved efficacy with reduced side effects compared with traditional chemotherapy. This review highlights the current landscape of targeted therapy in lung cancer, colorectal cancer, and prostate cancer, focusing on...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487969/

データ提供:米国国立医学図書館(NLM)

Targeted Therapy for Cancers: A Journey Through the Desert of Disease

In the vast desert of cancer research, targeted therapy is like a precious oasis, offering hope and relief from the relentless sandstorms of disease. Traditional chemotherapy, while sometimes effective, can be like a harsh desert wind, often causing significant side effects. Targeted therapy, on the other hand, aims to specifically target the cancer cells, minimizing collateral damage to healthy tissues. The authors of this review present a comprehensive overview of the current landscape of targeted therapy for lung, colorectal, and prostate cancers, highlighting key molecular targets and discussing FDA-approved drugs and promising candidates.

The review focuses on a range of targets, including the epidermal growth factor receptor (EGFR) and anaplastic lymphoma kinase (ALK) in lung cancer, vascular endothelial growth factor (VEGF) and EGFR in colorectal cancer, and the androgen receptor (AR) in prostate cancer. The review also explores promising targets like MET, ROS1, BRAF, and PARP, which are being investigated in clinical trials. This comprehensive analysis provides a detailed map of the desert of targeted therapy, outlining the current state of the art and the exciting possibilities for future research.

A New Era of Precision Medicine

The development of targeted therapies marks a new era in cancer treatment, where precision medicine is becoming the norm. This personalized approach, like customizing a camel caravan for specific desert conditions, allows for more effective treatments with fewer side effects. This study highlights the tremendous progress made in understanding the molecular mechanisms of cancer and the exciting potential of targeted therapies to improve patient outcomes.

A Hopeful Oasis in the Desert of Cancer

The study's findings offer a glimmer of hope for patients battling cancer. Targeted therapies, like a refreshing oasis in the desert, provide a path toward more effective treatments with fewer side effects. This approach allows for a more personalized experience, tailoring treatment to the specific needs of each patient. However, it is important to remember that targeted therapy is not a silver bullet, and ongoing research is crucial for advancing these treatments further.

Dr. Camel's Conclusion

The desert of cancer research is vast and complex, but targeted therapy is like a shining beacon, offering hope and possibility. This review provides a detailed map of the current landscape, highlighting the tremendous progress made and the exciting potential of targeted therapy to improve patient outcomes. As we continue to explore this new frontier, we can look forward to discovering even more oases of hope in the fight against cancer.

Date :
  1. Date Completed 2023-09-11
  2. Date Revised 2023-09-11
Further Info :

Pubmed ID

37686423

DOI: Digital Object Identifier

PMC10487969

Related Literature

SNS
PICO Info
in preparation
Languages

English

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