Paper Details

  1. Home
  2. Paper Details

Pooled Phase 2 and 3 Efficacy and Safety Data on Budesonide Oral Suspension in Adolescents with Eosinophilic Esophagitis.

Author: BoulesMena, CollinsMargaret H, DellonEvan S, DesaiNirav K, FalkGary W, GoldBenjamin D, GuptaSandeep K, HiranoIkuo, KatzkaDavid A, MukkadaVincent A, WilliamsJames, ZhangWenwen

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Budesonide oral suspension (BOS) was found to be effective in treating eosinophilic esophagitis (EoE) in adolescents. BOS improved histologic, dysphagia symptom, and clinicopathologic responses compared to placebo.
Paper Details　
Original Abstract of the Article :
OBJECTIVES: The objective of this study was to evaluate the efficacy and safety of budesonide oral suspension (BOS) in adolescents with eosinophilic esophagitis (EoE). METHODS: This post hoc analysis pooled data from two 12-week, randomized, double-blind, placebo-controlled studies of BOS 2.0 mg tw...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10642696/

データ提供：米国国立医学図書館（NLM）

Budesonide Oral Suspension: A New Hope for Adolescents with Eosinophilic Esophagitis

This research dives deep into the world of eosinophilic esophagitis (EoE), an inflammatory condition affecting the esophagus. It investigates the efficacy and safety of budesonide oral suspension (BOS) in adolescents with EoE. The study employs a rigorous approach, combining data from two randomized controlled trials. The authors provide compelling evidence that BOS is a safe and effective treatment for EoE in adolescents, offering a much-needed therapeutic option for this challenging condition.

Effective Treatment for Eosinophilic Esophagitis in Adolescents

The study's findings demonstrate that BOS significantly improves histologic and clinical responses in adolescents with EoE. It's like a soothing balm for the inflamed esophagus, reducing inflammation and improving the quality of life for these young patients. The study also highlights the safety profile of BOS, demonstrating its well-tolerated nature. This is encouraging news for families and caregivers who are grappling with EoE in their adolescents.

Improved Quality of Life for Adolescents with EoE

Imagine a desert oasis where the air is filled with dust and sand, making it difficult to breathe. EoE can be like this for adolescents, making it challenging to swallow and enjoy food. BOS acts like a gentle desert wind, clearing the air and restoring the ability to breathe and swallow comfortably. This can significantly improve the quality of life for these young people, allowing them to enjoy their meals and socialize without discomfort.

Dr. Camel's Conclusion

The results of this study are a ray of hope in the desert of EoE. BOS provides a safe and effective treatment for adolescents with this condition, offering them a chance to live healthier and happier lives. It's a reminder that even in the most challenging situations, there is always hope on the horizon.

Date :
  1. Date Completed n.d.
  2. Date Revised 2023-11-15
Further Info :

Pubmed ID

37718471

DOI: Digital Object Identifier

PMC10642696

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.