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Efficacy of ESHAP versus ICE plus dexamethasone (DICE) as salvage chemotherapy for relapsed or refractory diffuse large B-cell lymphoma.
Author: BoonlerdPattamaporn, Chai-AdisaksophaChatree, HantrakoolSasinee, HantrakunNonthakorn, NorasetthadaLalita, PiriyakhuntornPokpong, PunnachetTeerachat, RattanathammetheeThanawat, RattarittamrongEkarat, TantiworawitAdisak
Original Abstract of the Article :
OBJECTIVES: To compare the efficacy and side effects of salvage chemotherapy between etoposide, methylprednisolone, cytarabine and cisplatin (ESHAP) and ifosfamide, carboplatin and etoposide plus dexamethasone (DICE) for relapsed or refractory diffuse large B-cell lymphoma (DLBCL). METHODS: Medical...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521335/
データ提供:米国国立医学図書館(NLM)
Comparing ESHAP and DICE Regimens for Relapsed or Refractory DLBCL
The battle against cancer is a constant struggle, and finding effective treatments for relapsed or refractory diffuse large B-cell lymphoma (DLBCL) is a crucial endeavor. This study, exploring the realm of hematology, compares the efficacy and side effects of two salvage chemotherapy regimens: ESHAP and DICE, for patients with relapsed or refractory DLBCL.
ESHAP vs. DICE: Efficacy and Side Effects
The study, conducted through a retrospective review of medical records, revealed that both ESHAP and DICE regimens demonstrated comparable efficacy in terms of two-year progression-free survival, two-year overall survival, and overall response rate. However, the DICE regimen was associated with fewer renal adverse events than ESHAP. The findings highlight the need for a personalized approach to treatment decisions, considering individual patient factors and potential side effects.
Understanding the Landscape of Cancer Treatment
This research emphasizes the importance of tailoring treatment plans based on specific patient characteristics and the potential for side effects. The study reminds us that the quest for effective and tolerable treatments for relapsed or refractory cancers continues, and ongoing research is crucial for improving outcomes for patients.
Dr.Camel's Conclusion
Think of it like a camel navigating a treacherous sandstorm. A wise camel chooses the path that offers the best chance of survival, just as a physician must carefully consider the risks and benefits of different treatment options for their patients. This research underscores the importance of ongoing research and personalized approaches to cancer treatment, in hopes of finding a clear path to a healthy destination for those facing this challenging disease.
Date :
- Date Completed 2023-09-27
- Date Revised 2023-10-09
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