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New treatment opportunities for older patients with acute myeloid leukemia and the increasing importance of frailty assessment - An oncogeriatric perspective.

Author: DiekmannBenno, FrankenBas, HempeniusLiesbeth, HoogendoornMels, TimmermanMarjolijn, van RoonEric

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This review discusses the use of targeted chemotherapy drugs for treating acute myeloid leukemia (AML). These drugs have improved survival rates but can also have side effects.
Paper Details　
Original Abstract of the Article :
With the introduction of targeted chemotherapy drugs, a new age of treatment for acute myeloid leukemia (AML) has begun. The promotion of the azacitidine+venetoclax combination regimen to first line of treatment in patients deemed ineligible for intensive chemotherapy marks the first of many novel c...See full text at original site
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引用元：
https://doi.org/10.1016/j.jgo.2023.101631

データ提供：米国国立医学図書館（NLM）

New Hope for Older Patients with AML: A Focus on Frailty Assessment

Acute myeloid leukemia (AML) is a serious blood cancer that can be particularly challenging to treat in older patients. This research explores the impact of new targeted chemotherapy drugs and the importance of frailty assessment in this patient population. The study highlights the potential benefits and challenges of novel combination regimens for AML, emphasizing the need for careful consideration of patient frailty and comorbidities. Authors recommend a collaborative approach between hematologists and geriatricians to optimize treatment decisions and improve outcomes for older AML patients.

Navigating New Therapies for AML: The Importance of Frailty Assessment

This study emphasizes the importance of a comprehensive assessment of frailty in older patients with AML. Frailty can influence treatment tolerance, risk of complications, and overall outcomes. By carefully considering frailty status, healthcare professionals can make more informed treatment decisions, tailoring therapies to individual patient needs and optimizing their chances of success.

Optimizing Treatment for Older AML Patients: A Multidisciplinary Approach

The study highlights the importance of a multidisciplinary approach to managing AML in older patients. Collaboration between hematologists and geriatricians can ensure that treatment decisions are made with careful consideration of patient frailty, comorbidities, and overall quality of life. This integrated approach can lead to more effective and compassionate care for older AML patients.

Dr.Camel's Conclusion

Just as a camel can withstand harsh desert conditions with its unique adaptations, older AML patients require a tailored approach to treatment. This study underscores the importance of frailty assessment and multidisciplinary care in optimizing treatment decisions and ensuring the best possible outcomes for these individuals. It's a journey toward a future where we can provide more compassionate and effective care for vulnerable patient populations.

Date :
  1. Date Completed n.d.
  2. Date Revised 2023-10-02
Further Info :

Pubmed ID

37783588

DOI: Digital Object Identifier

10.1016/j.jgo.2023.101631

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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