Iatrogenic Cushing's syndrome in a case of allergic bronchopulmonary aspergillosis treated with oral itraconazole and inhaled budesonide.

Author: GargVipul Kumar, MaturuVenkata Nagarjuna, PrasadVirender Pratibh, TickooVidya

Paper Details 
Original Abstract of the Article :
Allergic bronchopulmonary aspergillosis (ABPA) is a hypersensitivity reaction to <i>Aspergillus fumigatus</i> that occurs in patients with asthma or cystic fibrosis. Here, we report a case of a young female with bronchial asthma who presented to our hospital with worsening breathlessness on exertion...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10565246/

データ提供:米国国立医学図書館(NLM)

Iatrogenic Cushing's Syndrome in a Case of Allergic Bronchopulmonary Aspergillosis

This case report describes a patient with Allergic Bronchopulmonary Aspergillosis (ABPA), a hypersensitivity reaction to Aspergillus fumigatus. The patient, diagnosed with ABPA, was prescribed a combination of oral itraconazole and inhaled budesonide. Despite initial improvement in symptoms, the patient developed features consistent with Cushing's syndrome, a condition caused by excessive cortisol production. Further investigations revealed that the combination of inhaled corticosteroid and oral itraconazole had led to iatrogenic Cushing's syndrome, highlighting the potential for drug interactions and the importance of careful monitoring during treatment.

Unveiling the Hidden Dangers of Drug Interactions

This case report serves as a stark reminder of the potential for unexpected drug interactions, even in commonly prescribed medications. Imagine a vast desert landscape, where seemingly harmless plants can harbor dangerous toxins. Just as a desert traveler must be aware of potential hazards, healthcare professionals must be vigilant about the possible interactions between medications.

The Importance of Careful Monitoring

This case underscores the importance of careful monitoring during treatment, particularly when combining medications. Just as a skilled desert navigator relies on frequent checks to ensure they are on the right course, healthcare providers must continuously monitor patients for any signs of adverse effects or drug interactions. This vigilance is essential for ensuring patient safety and optimal treatment outcomes.

Dr.Camel's Conclusion

This case report, like a lone traveler discovering a hidden oasis, reveals the potentially dangerous interactions between seemingly unrelated medications. The unexpected development of Cushing's syndrome underscores the importance of careful monitoring and vigilance during treatment, reminding us that even in the familiar landscape of medicine, unexpected dangers can lurk.

Date :
  1. Date Completed 2023-11-02
  2. Date Revised 2023-11-02
Further Info :

Pubmed ID

37813554

DOI: Digital Object Identifier

PMC10565246

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.