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Withdrawal from 3-Fluoroethamphetamine induces hyperactivity and depression-like behaviors in male mice.

Author: ChoiSun Ok, JoCheolmin, JooHyejin, LimNa Young, ParkSu-Jeong

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study investigated the short-term consequences of 3-Fluoroethamphetamine (3-FEA) administration in mice. 3-FEA administration led to physical dependence, demonstrated by withdrawal score increase and significant changes in hyperactivity and depression-like behavior following repeated administration and drug cessation.
Paper Details　
Original Abstract of the Article :
3-Fluoroethamphetamine (3-FEA) belongs to the amphetamine class of stimulant drugs and functions as a releasing agent for the monoamine neurotransmitters norepinephrine, dopamine, and serotonin. 3-FEA acts on the central nervous system and elicits physical and mental side effects, such as euphoria, ...See full text at original site
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引用元：
https://doi.org/10.1002/jnr.25251

データ提供：米国国立医学図書館（NLM）

The Hidden Depths of 3-Fluoroethamphetamine: Withdrawal Effects on Mice

The world of psychoactive substances is a complex and often dangerous territory. This study, like a scientist carefully observing a delicate ecosystem, explores the short-term consequences of 3-fluoroethamphetamine (3-FEA) withdrawal in mice. The researchers examined the behavioral changes and potential for physical dependence following repeated administration of this stimulant drug, highlighting the need for caution and understanding of its potential risks.

Unveiling the Shadows of 3-FEA Withdrawal

The study revealed that 3-FEA administration can lead to both hyperactivity and depression-like behaviors in mice. It's like a desert storm that disrupts the balance of a fragile ecosystem, causing unpredictable changes in behavior. The researchers observed significant changes in hyperactivity and increased immobility time, suggesting a potential for physical dependence and a range of withdrawal symptoms.

Awareness and Regulation: Protecting Ourselves from the Dangers of 3-FEA

This study serves as a reminder of the potential risks associated with 3-FEA. It's like a warning sign in the desert, alerting us to the dangers of traversing unfamiliar territory. The researchers highlight the need for awareness and regulatory action to control the use of this new psychoactive substance, protecting both individuals and communities from its potential harm.

Dr. Camel's Conclusion

This research sheds light on the complexities of 3-FEA and its potential for dependence and withdrawal. It's like uncovering a hidden oasis that is both beautiful and dangerous. This study underscores the importance of ongoing research to better understand the effects of new psychoactive substances and to develop strategies to protect public health. By learning from these studies, we can navigate the shifting sands of the psychoactive substance landscape and safeguard our well-being.

Date :
  1. Date Completed n.d.
  2. Date Revised 2023-10-11
Further Info :

Pubmed ID

37818759

DOI: Digital Object Identifier

10.1002/jnr.25251

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Languages

English

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