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Effects of norethindrone on the growth, behavior, and thyroid endocrine system of adult female western mosquitofish (Gambusia affinis).
Author: GuoYanfang, HouLiping, LiHaisheng, LiangXiaorou, LiangYan-Qiu, QiTang, YeMeixin, YuHongjun, ZouHong
Original Abstract of the Article :
Progestins are mainly used in pharmacotherapy and animal husbandry and have received increasing attention as they are widely detected in various aquatic ecosystems. In this study, adult female western mosquitofish (Gambusia affinis) were exposed to different concentrations of norethindrone (NET) (so...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1016/j.ecoenv.2023.115630
データ提供:米国国立医学図書館(NLM)
Norethindrone: A Silent Threat to the Fishy Social Scene?
We're exploring the fascinating world of aquatic ecosystems and the impacts of pharmaceuticals, a field known as ecotoxicology. This research focuses on the effects of norethindrone, a common synthetic progestin, on western mosquitofish, a small but mighty species playing a crucial role in aquatic environments. Researchers meticulously exposed these fish to various concentrations of norethindrone for 42 days, diligently observing changes in behavior, morphology, and the intricate workings of the thyroid endocrine system. They used a combination of experimental techniques including behavioral analysis, histological examination, and gene expression profiling.
The results, my friend, are intriguing. Norethindrone appears to dampen the social spirit of these fish, causing them to be less sociable and increasing their anxiety. Imagine, a fish with an existential crisis! This could have far-reaching implications for the overall social structure and dynamics of these fish populations.
Norethindrone: A Delicate Dance with Thyroid Hormones
The researchers also discovered that norethindrone plays a rather disruptive role in the delicate balance of thyroid hormones. This is crucial as thyroid hormones, like a symphony conductor, regulate various bodily functions. Exposure to norethindrone triggered changes in thyroid gland structure and altered the levels of key thyroid hormones, like TSH, T3, and T4, hinting at a potential disruption in the intricate symphony of thyroid function.
Norethindrone: A Cautionary Tale for Our Aquatic Ecosystems
These findings raise important concerns about the impact of pharmaceuticals on our aquatic environments. The presence of synthetic hormones like norethindrone in our waterways could be a silent threat, potentially disrupting the delicate balance of aquatic ecosystems and the well-being of the creatures that inhabit them.
Dr.Camel's Conclusion
This research serves as a reminder that our actions, from the pharmaceuticals we consume to the waste we generate, can have far-reaching consequences for the environment. It's time to pay attention to the silent whispers of our aquatic ecosystems and take steps to protect these vital environments.
Date :
- Date Completed 2023-11-21
- Date Revised 2023-11-21
Further Info :
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