Paper Details 
Original Abstract of the Article :
In recent years, highly selective reversible CDK4/6 inhibitors have been combined with aromatase inhibitors for their efficacy and ease of application in the treatment of advanced stage of hormone-responsive breast cancers. Oral use of these drugs facilitates patient compliance. However, adverse dru...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1177/10781552231208390

データ提供:米国国立医学図書館(NLM)

Ribociclib and Liver Toxicity: A Case Study

This report highlights a case of liver toxicity associated with the use of ribociclib, a CDK4/6 inhibitor commonly used in combination with aromatase inhibitors for the treatment of hormone-responsive breast cancers. The study underscores the potential risks of using ribociclib, despite its efficacy and ease of administration.

The authors describe the case of a postmenopausal woman with metastatic hormone receptor-positive breast cancer who experienced liver toxicity while taking ribociclib. This case report adds to the existing literature on adverse drug reactions associated with ribociclib, including skin reactions, liver toxicity, and vitiligo.

Navigating Treatment Options: Balancing Benefits and Risks

This case study highlights the importance of careful monitoring and prompt intervention when patients are taking ribociclib. While ribociclib can be a valuable treatment option for breast cancer, clinicians must be aware of its potential side effects and tailor treatment plans accordingly to ensure patient safety.

Health and Lifestyle: Vigilance and Early Intervention

Individuals undergoing treatment with ribociclib should be aware of the potential for liver toxicity and other adverse reactions. Regular monitoring of liver function is crucial to detect early signs of problems. It is essential to have open communication with your healthcare provider to discuss any concerns or changes in health status during treatment.

Dr.Camel's Conclusion

This research reminds us that even seemingly effective treatments can have unexpected side effects. It's like navigating a desert oasis; while it offers respite, it also requires vigilance to avoid any hidden dangers. This case study emphasizes the importance of careful monitoring, prompt intervention, and open communication between patients and their healthcare providers.

Date :
  1. Date Completed n.d.
  2. Date Revised 2023-10-30
Further Info :

Pubmed ID

37899576

DOI: Digital Object Identifier

10.1177/10781552231208390

Related Literature

SNS
PICO Info
in preparation
Languages

English

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