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Phenytoin-Associated Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis Overlap in Focus: A Case Report.
Author: AslamZaid M, ChitkaraAkshit, KomalFnu, PrachiFnu, PuriPiyush, SardanaPrincy
Original Abstract of the Article :
Stevens-Johnson syndrome and toxic epidermal necrolysis overlap is a rare but severe cutaneous hypersensitivity reaction that can lead to death if not treated aggressively and adequately. Drug-induced hypersensitivity reactions are often related to drug exposure, with sulfonamides, anti-epileptics, ...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604504/
データ提供:米国国立医学図書館(NLM)
Phenytoin: A Case of Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis Overlap
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are serious and potentially fatal skin reactions. This case report explores the occurrence of SJS/TEN overlap in a young boy following the administration of phenytoin, a medication used to treat seizures. The report provides a detailed account of the patient’s experience, highlighting the importance of recognizing and managing this life-threatening condition.
A Rare and Devastating Reaction
The case report highlights the rare but potentially fatal nature of SJS/TEN overlap. This adverse drug reaction is a severe form of hypersensitivity reaction, characterized by widespread blistering and shedding of the skin. The report emphasizes the importance of early recognition and prompt management to minimize complications and improve patient outcomes.
Navigating the Sands of Risk
This case report underscores the importance of careful drug selection and monitoring for potential adverse reactions. It serves as a stark reminder of the potential risks associated with medications, even those commonly prescribed for serious conditions like seizures. It’s like navigating a desert filled with hidden dangers – we must be vigilant and prepared to respond quickly to any unexpected events.
Dr. Camel's Conclusion
This case report serves as a poignant reminder of the potential dangers associated with medications. It underscores the importance of careful drug selection, monitoring for adverse reactions, and prompt management in the event of a serious adverse event. It’s like navigating the desert – we must always be aware of the potential for danger and be prepared to adapt our course as needed.
Date :
- Date Completed n.d.
- Date Revised 2023-10-31
Further Info :
Related Literature
English
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