Anastrozole as a therapeutic option for gynecomastia in a person receiving antiretroviral therapy: Case report.

Author: AntoniadiChristina, BoffitoMarta, CandelaCaterina, GebreselassieAbeba, SenkoroElizabeth, VaradarajanMaithili

Paper Details 
Original Abstract of the Article :
A middle-aged Caucasian man living with HIV, clinically stable (viral load <20 copies/mL) on injectable antiretroviral cabotegravir plus rilpivirine every 2 months presented with a 6-month history of bilateral enlargement of the breasts associated with pain. His hormonal profile was normal, and no o...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1111/bcp.15951

データ提供:米国国立医学図書館(NLM)

Gynecomastia in HIV Patients: A Challenging Terrain

This case report explores the complexities of managing gynecomastia, a condition characterized by breast enlargement, in a patient living with HIV. The authors present a case of a middle-aged man experiencing gynecomastia while on antiretroviral therapy with cabotegravir and rilpivirine. They discuss the challenges of using tamoxifen, a commonly used anti-estrogen for gynecomastia, due to its potential interaction with antiretroviral medications.

Anastrozole: A Potential Solution

The authors describe the use of anastrozole, an aromatase inhibitor, as a therapeutic option for gynecomastia in their patient. Anastrozole, unlike tamoxifen, does not induce cytochrome P450 3A4 (CYP3A4), minimizing the risk of drug interactions with antiretrovirals. This case report offers a potential solution for managing gynecomastia in HIV patients, allowing for effective treatment while maintaining virological control.

Navigating the Desert of HIV Management

Managing HIV and its associated conditions can be like navigating a vast and unforgiving desert. This case report highlights the importance of finding safe and effective solutions for managing gynecomastia in HIV patients. By understanding the potential risks and benefits of different treatment options, we can better navigate the complexities of managing this condition while maintaining the overall health of our patients.

Dr.Camel's Conclusion

Managing gynecomastia in HIV patients can be a tricky endeavor, like finding a safe path through a desert filled with potential pitfalls. This case report offers a valuable insight into the potential benefits of anastrozole, providing hope for a safer and more effective treatment option for this challenging condition.

Date :
  1. Date Completed n.d.
  2. Date Revised 2023-11-17
Further Info :

Pubmed ID

37917870

DOI: Digital Object Identifier

10.1111/bcp.15951

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.