Review of Intra-Articular Use of Antibiotics and Antiseptic Irrigation and Their Systematic Association with Chondrolysis.

Author: BlankespoorMichael G, IerulliVictoria K, MoreyTucker D, MulcaheyMary K, PostHunter K, SchroeppelJ Paul, VopatBryan G, VopatMatthew L

Paper Details 
Original Abstract of the Article :
Label="Introduction" NlmCategory="UNASSIGNED">Intra-articular antibiotics have been proposed as a treatment for septic arthritis to allow for high local concentrations without subjecting a patient to the toxicity/side effects of systemic therapy. However, there is concern for chondrotoxicity with in...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635690/

データ提供:米国国立医学図書館(NLM)

Intra-Articular Antibiotics: A Balancing Act in Septic Arthritis

Septic arthritis, a serious infection of the joint, often requires aggressive treatment to prevent lasting damage. This systematic review delves into the use of intra-articular antibiotics, medications delivered directly into the joint, to address this challenging condition. The authors examine the potential benefits and risks of this treatment approach, particularly concerning the potential for chondrotoxicity, damage to the cartilage. The review explores the existing literature, analyzing the association between intra-articular antibiotic use and chondrolysis, a condition characterized by cartilage breakdown. The authors emphasize the importance of balancing the benefits of intra-articular antibiotics with the potential risks, particularly in the context of chondrotoxicity.

Intra-Articular Antibiotics: Weighing the Risks and Benefits

This systematic review underscores the importance of carefully considering the risks and benefits of intra-articular antibiotics in managing septic arthritis. The authors' findings highlight the potential for chondrotoxicity, emphasizing the need for cautious use and ongoing monitoring.

Navigating the Complexities of Septic Arthritis

Septic arthritis is a serious condition that can lead to significant joint damage and disability. This review provides valuable insights into the use of intra-articular antibiotics, a treatment approach that offers potential benefits but also carries risks. The authors' findings encourage clinicians to weigh the risks and benefits carefully, ensuring that this treatment is used appropriately and monitored closely.

Dr. Camel's Conclusion

This systematic review delves into the complexities of using intra-articular antibiotics for septic arthritis. The authors highlight the potential benefits of this treatment approach, but also emphasize the need to carefully consider the risks of chondrotoxicity. Just as a camel navigates the desert landscape with caution and awareness of its surroundings, clinicians must carefully assess the risks and benefits of intra-articular antibiotics, ensuring that this treatment is used appropriately and monitored closely. This review serves as a valuable resource for clinicians, encouraging further research into the long-term effects of intra-articular antibiotics and the development of safer alternatives.
Date :
  1. Date Completed n.d.
  2. Date Revised 2023-11-22
Further Info :

Pubmed ID

37954883

DOI: Digital Object Identifier

PMC10635690

Related Literature

SNS
PICO Info
in preparation
Languages

English

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