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Acrofacial vitiligo secondary to PI3KCA inhibitor, alpelisib: case report.
Author: HijabAdham, HinichMaayan Geller
Original Abstract of the Article :
Alpelisib plus fulvestrant is a valid second or advanced line of treatment for patients with metastatic hormone receptor (HR)-positive, HER2-negative breast cancer who harbor an activating PIK3CA mutation. The well-known side effects of alpelisib are hyperglycemia, rash, and diarrhea. Herein, we rep...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10642942/
データ提供:米国国立医学図書館(NLM)
Alpelisib and the Unexpected Side Effect of Vitiligo
Alpelisib, a medication used for treating certain types of breast cancer, is generally well-tolerated, but can sometimes cause unexpected side effects. This case report describes an unusual instance of a patient developing acrofacial vitiligo, a condition characterized by depigmentation of the skin, after starting treatment with alpelisib. This finding raises important questions about the potential dermatological side effects of alpelisib and the need for careful monitoring of patients undergoing treatment with this medication.
Alpelisib and the Potential for Vitiligo
This case report highlights the importance of being vigilant about potential side effects of medications, even those considered relatively safe. The patient's development of acrofacial vitiligo after starting alpelisib suggests a possible link between the medication and this dermatological condition. Further research is needed to confirm this association and to better understand the mechanisms underlying this side effect.
Navigating the Treatment of Breast Cancer
As a doctor, I understand the importance of balancing treatment effectiveness with potential side effects. This case report reminds us that even medications considered safe can have unexpected consequences. It emphasizes the need for open communication between doctors and patients, ensuring that patients are fully informed about potential risks and benefits of their treatment options.
Dr.Camel's Conclusion
Alpelisib, a medication used to combat breast cancer, is like a desert oasis offering hope for patients. However, like the unpredictable desert, sometimes unexpected challenges arise. This case report reminds us to be observant, just as a camel navigates the desert, and to remain vigilant for potential side effects, ensuring the best outcomes for our patients.
Date :
- Date Completed n.d.
- Date Revised 2023-11-16
Further Info :
Related Literature
English
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