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Drug-drug interactions and the risk of adverse drug reaction-related hospital admissions in the older population.
Author: BennettKathleen E, CahirCaitriona, HughesJohn E, MoriartyFrank
Original Abstract of the Article :
To estimate potentially clinically important drug-drug interaction (DDI) prevalence, the average causal effect of DDI exposure on adverse drug reaction (ADR)-related hospital admission, and examine differences in health-related quality of life (HRQoL) and length of stay (LOS) per DDI exposure in an ...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
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引用元:
https://doi.org/10.1111/bcp.15970
データ提供:米国国立医学図書館(NLM)
Drug-Drug Interactions: A Complex Landscape in the Desert of Geriatrics
The aging population presents unique challenges in managing drug-drug interactions (DDIs), which can lead to adverse drug reactions (ADRs) and increase the risk of hospitalization. This study explores the prevalence of DDIs, their causal effect on ADR-related hospital admissions, and their impact on health-related quality of life (HRQoL) and length of stay (LOS) in an older population. The researchers conducted a retrospective analysis of hospital admission data, focusing on individuals aged 65 years and older. Their findings highlight the significant prevalence of DDIs, demonstrating a causal link between DDI exposure and ADR-related hospital admissions. The study also underscores the negative impact of DDIs on HRQoL and LOS, emphasizing the importance of careful medication management in older adults.
DDIs: A Hidden Danger in the Desert of Geriatrics
The study's findings emphasize the critical importance of addressing DDIs in older adults. The prevalence of these interactions and their causal link to ADR-related hospital admissions underscore the need for comprehensive medication management strategies. Healthcare providers must be vigilant in identifying potential DDIs, carefully reviewing medication lists, and monitoring for signs of ADRs.
Navigating the Desert of Medication Management
This study highlights the challenges of medication management in older adults, particularly in relation to DDIs. Careful attention to medication history, regular monitoring for ADRs, and collaboration between healthcare providers and patients are crucial for minimizing the risks associated with DDIs. Educating patients about potential drug interactions and the importance of reporting any adverse effects can empower them to actively participate in their medication management.
Dr.Camel's Conclusion
Just as a wise camel navigates a treacherous desert landscape, we must approach medication management in older adults with caution and foresight. This study underscores the importance of identifying and mitigating potential DDIs, ensuring the safe and effective use of medications in this vulnerable population.
Date :
- Date Completed n.d.
- Date Revised 2023-11-20
Further Info :
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